Faith says, "Nobody's smoked a cigar in here since the last time Letterman was here." This is a joke at the long-running laugh-about feud between Regis Philbin and David Letterman.
Lori Schulweis, (un-credited in this episode), is seen laughing when Hal and Faith are auditioning for Good Morning Glen Falls. She is their real producer on Live with Regis and Kelly.
During the audition for Good Morning Glen Falls, Faith (Kelly Ripa) makes a reference to Hal's toenails. This is an in-joke during a pedicure that Kelly had to give to Regis during an episode of Live with Regis and Kelly where Kelly lost a bet. While she was removing Regis' shoes, she made constant jokes about how long and ugly his toenails were.
Hal: Wait! I haven't plugged my CD yet!
Regis is, referring to his Christmas CD that he constantly plugged from September to December of 2005 during Live.
(Faith throws Handsome Hal's cigar and lighter out the window)Hal: Hey, that's my lifeline!
Regis Philbin (Hal) used to be the host of the game show Who Wants to be a Millionaire, which features lifelines to help the contestants out.