This is another repetition of the House formula : misdiagnose, blame patients, test procedures, or fellow doctors, and repeat until patient dies or gets better.
In this case, it's a patient who is misdiagnosed with ALS, and asks for a "Do Not Resusitate" (DNR). House thinks he doesn't have ALS, and that he's not capable of thinking objectively. When House gives him medicine that creates breathing difficulties, he violates the DNR and incubates the patient.
House believes he has another condition entirely (but is wrong). The patient's original doctor belives he has ALS (but is wrong). They all fight over the right to pull the plug, and the patient get's better seemingly on his own (in spite of the excellent care House gives him).
Eventually House realises his diagnosis was wrong, again. And in the end, find's the right diagnosis and treatment. He has a greatful patient, and some degree of validation.
But he's alienated his staff, with almost inexcusable hubris. It seems I'm not the only one frustrated by the frequency of his mistakes, and his arrogance.