House

Workers at a factory are discussing their relationship when their co-worker arrives: Sophia, a 16-year old. As she talks to the guy, Doug, Sophia clutches at her chest and falls onto the conveyer belt heading toward the press. They stop it just in time as she starts coughing up blood.

House comes into work and Wilson concludes that he didn't ask Cuddy out. When Wilson doesn't comment, House suspects something is up. The team takes on the case and Kutner explains that Sophia is an emancipated minor working at the factory Foreman suggests Sophia is pregnant. Kutner doesn't believe it, or that she's taking drugs as Thirteen suggest. House orders Kutner and Foreman to do an echo and Foreman asks to be let go temporarily to do clinical trials. House refuses to let him, claiming that he might need him.

Kutner gives the echo test to Sophia and tries to let her know that he understands. She isn't impressed but he notes that his parents died when he was six and he knows how she feels.

Taub and Thirteen go over Sophia apartment and find a bong. Thirteen is skeptical of Kutner's trusting nature and Taub insists that some trust is necessary. Kutner suggests that Sophia needs steroids for vasculitis but House tells Foreman to put her on beta-blockers. Foreman tells the rest of the team to take care of it and leaves. Kutner administers the beta-blockers and Sophia claims the bong belonged to her ex. She admits they have no reason to trust her, and Kutner suggests she has vasculitis, but if she's using drugs the steroids could kill her. She insists she hasn't used drugs and Kutner goes to get the steroids.

Foreman goes to the clinic and Cuddy arrives to ask why he's there. She's not interested in overriding House and wonders if he's trying to prove something. Foreman checks out a young kid, Jonah, who is suffering from bloody vomit and diarrhea. His older brother Evan is surprisingly knowledgeable about medical procedure and thoughtful of his brother. Meanwhile, Sophia has a psychotic break and they sedate her, and Kutner admits that he gave her steroids.

The team stabilizes her and House blames Foreman for leaving it up to Kutner. Foreman suggests prinzmetal angina that caused an artery in the brain to spasm, and House reluctantly agrees, but orders Foreman to trigger an artery spasm. Foreman tells the team to set it up and page him when they're ready to actually run the procedure. He returns to check on Jonah and has him swallow a camera. Evan convinces him to do it and Foreman notes that he didn't treat his younger brother that nicely. Jonah starts giggling uncontrollably and Foreman has no idea why. He talks to Cameron and Chase and asks for a differential but Chase isn't interested. He informs them it isn't House's case and they decide to look at it, but Chase warns it won't be enough to prove anything. Foreman is called away as Kutner begins the procedure and talks about her parents being dead. Sophia's arteries are fine but he's able to tell from the blood flow that she's lying. Kutner is angry at her but she says she told the truth about not using drugs but lied about her parents because her father raped her and her mother didn't do anything about it.

Back in differential, House notes that the rape has nothing to do with the symptoms and therefore isn't of interest to them. Kutner suggests she might by lying about the rape and House notes that she might be suffering from emotional stress, explaining the symptoms. House orders them to give her anti-anxiety drugs and to make sure Foreman did it.

House talks with Wilson and explains what happened but Wilson isn't interested in giving opinions or insights. House is less than thrilled. Meanwhile, Chase and Cameron give a differential to Foreman but can't come up with anything major, while Cameron notes that Foreman needs to focus on one case or the other. He ropes them into testing Jonah and goes to see Sophia where Thirteen is giving her the treatment. She apologizes and Thirteen suggests she file a police report on the rape. Sophia refuses, saying she doesn't want to be labeled. However, Foreman realizes the drugs aren't helping: her urine has turned brown.

Back in differential, they wonder if the shredded red cells indicate an infection, but it doesn't correspond with her previous symptoms. House wonders about Sophia's homemade furniture and Thirteen says that there were holes, indicating they were pressure treated. Sawing the lumber would have released arson into the air, and Foreman suggests they test her hair as it wouldn't show in a bloodtest. He gets a page and leaves, raising House's suspicions. Foreman meets with Chase and Cameron, who reveal they haven't found anything. Chase says that he needs more help then they can provide but Foreman doesn't think they're at that point yet. Jonah goes into cardiac arrest and they're forced to revive him. Chase tells him they're at the point.

Thirteen removes the arsenic from Sophia's body with chelation and says she's free to go in the morning. Sophia wonders why she doesn't give her any advice. She finally gives in and asks Thirteen for her opinion, and Thirteen says that she's strong and can handle things. Sophia has a seizure and House concludes that the arsenic was fighting what is killing Sophia and tells them to put it back in. They figure it's acute leukemia but arsenic won't cure it: she needs a bone marrow donor. Foreman comes in and House knows about Jonah. Foreman said that Jonah needs House but House isn't interested. He tells Foreman that he wanted the case for himself, so now he has it. House confronts Wilson and figures that he's not doing anything to force House to deal with it. Wilson simply shrugs and agrees and goes on his way.

As they conduct a biopsy, Thirteen tells Sophia that the odds of her finding a suitable donor are better if she goes to her parents. Sophia would prefer to die then involve them in her life. Taub lies and says he has Huntington's, and says he'd do anything to stop it so he can make his life matter. Sophia asks if he's been raped and when he says no, she tells him he can't understand what she's going through. Thirteen is angry that Taub lied to Sophia using her disease, and Taub points out Thirteen never relates to Sophia personally. Thirteen angrily insists that they contact her parents even though Sophia doesn't want to, but House refuses. She says she plans to find Sophia's parents.

Cameron and Chase meet with Foreman and Foreman points out that Foreman has got what he wished for. Chase wonders if the mother or brother are involved. Foreman notes Jonah shares everything with his brother and gets an idea.

Thirteen goes to talk to Sophia's parents to test their suitability as bone marrow donors only to discover that their daughter Sophia is living with them… and it's a totally different girl. Thirteen confronts Sophia, saying she stole Sophia's identity. Sophia admits she did it to protect herself from her real parents and asks Thirteen to pretend she didn't find the girl. Thirteen tells her to call the parents so they determine their donor suitability, but Sophia refuses and notes that when she gets sick enough, they'll have to give her the transplant without parental consent.

Foreman has realized Jonah is suffering from an iron overdose: Evan gave his vitamins to Jonah. Evan is sorry but Foreman assures him that Jonah will get better and forgive him.

House arrives at work the next morning and the team has a partial match, but a partial could make it impossible for Sophia to receive a second donation if the first one fails. House tells them to treat Sophia no matter what. They note that she was rational first rather than emotional and House notes that it's unusual and wonders if she lied because something worse happened then rape. He goes to see Sophia and asks her what happened. He asks why she doesn't want pity and she insists she wants to be normal. He realizes she did something that makes her not want to live and asks what she did. Sophia refuses to answer, saying her parents won't care. When House snaps at her, she finally admits she killed her brother: he drowned in the bath when she was watching him. House tells her that if she dies by refusing treatment her parents will hate her for sure and there's one thing she can do to keep it from getting worse.

Sophia's parents come in to help her. Jonah and Evan leave with their mother, who hugs Foreman as she leaves. Kutner looks on as Sophia is reunited with her parents and breaks down crying.

Foreman confronts House and says he's going to do clinical trials, having proven he can handle two cases. House easily gives in and Foreman wonders why: House notes that before Foreman asked him, and this time he told House he was going to do it. As House gets in the elevator, Wilson gets in and finally says it was a nice thing he did for Foreman. Wilson explains that House needed to prove to Foreman he could handle it, but House points out it doesn't work the same for him. They see Cuddy as they're going out and House isn't interested in talking about her. Wilson says that he'll be okay.