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House: Who would you fire?
Dr. Cameron: No one.
House: Not an option.
Dr. Cameron: If everyone took a pay cut and put in a few more hours, we could all stay for the same amount of money.
House: Figures you'd try and come up with a solution where no one gets hurt. The problem is, the world doesn't work that way just 'cause you want it to.
Dr. Cameron: Figures you'd stall and refuse to deal with the issue. Problem is, the world doesn't go away just because you want it to.
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Dr. Cameron: I apologize if it looked like we weren't devoting our full attention to your daughter, but I assure you that we...
Mrs. Simms: Oh please, save your pathetic insincerity for your boyfriend.
House: You're wrong! She is in fact pathetically sincere.
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House: Men are pigs - you have nothing to worry about. They will pretty much have sex with anyone - young, old, heavy, thin, complete strangers, relatives.
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House: No, there's no time to think! Say the first thing that comes to your head.
Dr. Chase: She's fat.
Dr. Foreman: Enough already! We get it! You hate fat people!
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House: You have kids! How novel! That changes everything. So if Mommy has heartburn, one of them might catch on fire.
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Foreman: Have you seen the latest research?
Chase: Yes, I have. What I haven't seen lately is a kid eating an apple or riding a bike. You Americans can't even compete with the rest of the world in basketball anymore, unless, of course, it's the type you play with a remote control on a big screen TV.
Foreman: Right.
House: Wait! Are you going to let him say that? He insulted our basketball teams!
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Dr. Cameron (on taking diet pills): I can't believe she was that desperate.
House: Yeah, I'm sure that if everyone I knew hated me, I couldn't bear to look at me. I wouldn't go so far as to shoplift.
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Ms. Ayers: I understand, it's just, well, Jessica really doesn't have any friends.
Foreman: Not one?
Ms. Ayers: I've tried to help, make the kids include her more, but kids can be -
Foreman: Kids?
Ms. Ayers: Heh, I was going to say jerks.
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Chase: No, society tells you you have to be thin to be attractive. And guess what, that's what attractive means: that society likes looking at you.
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Foreman: And you figure making her feel like crap would do her a world of good?
Chase: Yeah, if it gets her off the couch!
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Lucille: This is what a woman is supposed to look like. Okay, we're not just skin and bones. We have flesh. We have curves.
House: You have little people inside you.
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Chase: She's morbidly obese. The "morbid" part of that raises alarms.
Foreman: Come on, it takes decades to eat your way into a heart attack.
Chase: Doesn't take decades to kill yourself. If I was that fat, I'd be pretty tempted to knock back a bottle of pills.
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Cuddy: You need to get rid of one of your people.
House: Absolutely. As soon as I do performance reviews. And then review the reviews, of course. Because a decision like this can't be made without proper, you know, review. Shouldn't take longer than a month, maybe two. Four at the most, unless it gets complicated.
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Mr. Hernandez: Tell her it's cancer – you obviously don't have a problem with lying.
House: Oh – way to win me over.
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House: Even if I was Dr. House, physician-patient confidentiality protects me from annoying conversations.
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House: Why would you support someone who screws up?
Dr. Cameron: Because I'm not insanely insecure. And because I can actually trust another human being. And I am not an angry misanthropic son of a bitch.
House: Sorry - you said you weren't angry.
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House: You wear a bikini now?
Lucille: Yeah - you have a problem with that?
House: No. I've never gone swimming with you.
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Dr. Cameron: No plastic surgeon in his right mind is going to give a 10-year old liposuction.
Dr. Chase: Have you ever met a plastic surgeon who was in their right mind?
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House: I'm thinking I can convince Vogler it'll be more cost-efficient to keep all of them.
Dr. Wilson: You should be able to pull that off. Most billionaires aren't very good with numbers.
House: It will be more cost-efficient once I grab Cameron's ass, call Foreman a spade, and Chase... well, I'll grab his ass too.
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Dr. Chase: Obesity isn't something you just grow out of.
Dr. Foreman: I take it you've never seen a baby.
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Lucille: I'm not pregnant!
House: Sorry, you don't get to make that call unless you have a stethoscope. Union rules.
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Lucille: It's like my heart is on fire. Like it's, oh I don't know, like...
House: Burning?
Lucille: Exactly!
House: Hmm. Sounds almost like heartburn.
Lucille: So can you give me something?
House: Like a thesaurus?
Lucille: What?
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House: You ever seen an infected pierced scrotum?
Dr. Cuddy: Uh, no, but I know a few people on whom I'd like to see it happen.
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Dr. Foreman: Ten-year-olds do not have heart attacks. It's got to be a mistake.
House: Right. The simplest explanation is she's a 40-year-old lying about her age. Maybe an actress trying to hang on.