House

A con man is running three-card monte on a woman who suddenly can't decide what card to select. She collapses and the guy runs off.

The woman, Lupe, wakes up and talks to Foreman who identifies her condition as TIA caused by abulia, causing her brain to "freeze." While Chase and Foreman discuss the fact she's a scam artist who goes from job to job to collect unemployment and whether it means she has drugs, House notices Wilson meeting with his ex-wife. Lupe's drug test proves clean and House goes off to talk to Wilson, who says his ex needs to have him take care of their dog, Hector. House is more interested with the fact Cuddy turned him down for a date to a play and Wilson reveals she is going out with him instead to an art gallery exhibit.

As Chase and Foreman leave to check out Lupe's apartment, they run into Foreman's father Rodney and he suggests that Foreman talk to his mother, who he's been avoiding for eight years and who has Alzheimer's. At Lupe's apartment they find drugs and Chase goes to run the tests, leaving Foreman to have to go to dinner with his parents.

House spars with Cuddy over her dating and she thinks he's jealous. Foreman arrives at his parents' hotel room and his mother is glad to see him. Later he returns to the hospital where Lupe starts coughing up blood and goes into respiratory arrest. Cameron and Chase run tests on her, and Chase notes he's still available despite Cameron's denials. They spot a mass and conclude she is auto-immune. Foreman recommends steroids and House agrees with the (boring) treatment. House then leaves to check out condos with Wilson's wife, Bonnie, a real estate agent. He not-so-subtly asks her about Wilson's dating habits. Meanwhile, Wilson and Cuddy go to an art exhibit and realize that they're at the wrong exhibit. The one they're at has exotic artwork. Bonnie wants House to persuade Wilson to take Hector while he keeps talking to her about her romantic and sexual relationship with Wilson.

While Foreman tends to Lupe, she figures out he doesn't like her because of her drug use, and she starts coughing again. He determines from the yellow in her eyes that her liver is failing and she'll need a transplant, and three of her organs are getting worse. Foreman now suspects cancer and proposes full radiation treatment. House agrees and goes to get her consent and discuss Foreman. She goes into brain freeze again then passes out.

House chats with Wilson who wants to know why he was talking to Bonnie. House says he plans to work out why Wilson keeps going wrong in his relationships and says he has to have sex with Cuddy: Wilson is not amused. As they prepare Lupe for radiation treatment, she starts screaming in pain from the pressure of the blood cuff.

The staff concludes she's septic as a result of the steroid treatment Foreman ordered, and he agrees to tell her what they've done. Later, Bonnie comes to see House to show him a new condo and he admits he doesn't plan to buy one. She confronts him saying that House never cared about her and he didn't help as far as her marriage breaking up. House is unapologetic and she leaves.

Foreman goes to Wilson on advice about how to break the news and he suggests that Foreman show her how upset he is. Foreman than goes to tell her that she has less than 24 hours and there's nothing they can do about it. She screams at him to get out. Outside, Foreman slams his fist into a wall in anger. He goes to Cameron to get his hand bandaged and finds out House is preparing an aspiration for her. Foreman goes to confront him as he tries to figure out what they missed. Foreman tells him to wait. He then goes to see Lupe who admits she has no friends and her passing won't make much difference. As they wait for her to die, Foreman admits she was right when she said earlier he had a problem with her, and that he made some bad decisions, then worked to overcome them. He concedes he still proves himself and when he went home in his last year of college, it was the last time he felt at home. She admits that she made things up about how she never had a chance as well.

Foreman watches over her as she dies, then calls in House to do his tests. Chase tries to comfort Foreman by suggesting he talk to God. House discovers she scratched herself with her bra hook, which let a staph infection get in. He breaks the news to Foreman who isn't comforted. House says it won't be Foreman's last mistake, or his.

House heads out with Wilson, and reveals that he's keeping Hector. Foreman meets with his mother and admits he hurt someone and it was his fault. She forgives him… but doesn't remember who he is.