Trivia: The operation to relieve Alfredo's right side paralysis (due to subarachnoid hemmorhage) was performed on the left side of his head. This is anatomically correct: the left side of the brain controls the right side of the body, and vice versa.
Stacy: (about House) Why is he so curious about Cuddy?
Dr. Wilson: Why are you so curious about his curiosity?
Stacy: Why are you so curious about me be...
Dr. Wilson: Because you dumped him and you're married and they are neither of those things.
Stacy: I'm just curious. Nothing wrong with that.
Dr. Wilson: No. Nothing wrong with that.
Dr. Foreman: You did exactly what white people do. You figure we don't need to know the truth, or can't understand it. So you just lie to us.
House: Just a white lie.
Dr. Foreman: Good one, 'massa.
Dr. Cuddy: What do you want, House?
House: If you're wallowing in self-loathing, I've got something that might help. We're getting sued!
Dr. Cuddy: Maybe we were right to begin with: his problems are all caused by DIC precipitated by falling off of my roof.
Dr. Chase: DIC wouldn't cause a fever this high.
House: See? My lapdog agrees with me.
House: Pinkies are supposed to be pink, right? I mean, they're not called "gray-ies."
Dr. Cuddy: But the organ failure is going to kill him!
House: But the pinkie is weirder
Dr. Cuddy: It's pneumonia. He wanted to go home. I thought he was lying. I sent him back up there.
House: Well why didn't you just take out a gun and shoot him?
House: You're not happy unless things are just right. Which means two things. You're a good boss. And you'll never be happy.
Dr. Cuddy: You figure a perverted sense of guilt makes me a good boss?
House: Now would the world be a better place if people never felt guilty? Makes sex better. (points to Stacy with his cane) Should have seen her in the last months of our relationship. Lot of guilt. Lot of screaming.
Dr. Cuddy: All this from falling off my roof…
House: Yeah, if only he'd fallen on his head. Then he wouldn't have any of these symptoms.
Dr. Chase: How did you know about that key?
House: Someone as insecure as Cuddy has to have 20 keys in a 15-foot radius.
Dr. Cuddy: He lose that hand, he loses his job. All of his jobs. He's not like us.
House: He can't work as a cripple?
Dr. Cuddy: He loses his home, his kid brother drops out…
House: American dream destroyed. Very sad, very emotional. Not one medical fact in the whole pathetic tale. You've lost perspective, Cuddy. You've stopped looking at this as a doctor. You're acting like someone who shoved somebody off their roof. You want to make things right? Too bad. Nothing's ever right.
Robert: Look. My heart's red, your heart's red. And it don't make no sense to give us different drugs.
House: You know, I have found a difference. Admittedly, it's a limited sample, but it's my experience in the last ninety seconds that all black people are morons. Sorry, African-Americans.
Robert: I'll see another doctor.
House: Fine. Fine. I'll give you the same medicine we give Republicans.
Robert: I'm not buying into no racist drug, okay?
House: It's racist because it helps black people more than white people? Well, on behalf of my peeps, let me say, thanks for dying on principle for us.
House: (to Cuddy) If I tried a scheme like this, you'd get that nasty wrinkly face and screech like a hyena. Very sexy, I admit.
Dr. Cuddy: Why didn't you say you speak Spanish?
House: Because she'd want to talk to me.
House: (about Cuddy) I'm happy to report we're so in sync we're wearing each others underwear.
Dr. Cuddy: Are you being intentionally dense?
House: Oh my God. She's got pictures of you in here. Just you and…it's like some kind of weird shrine.
Dr. Chase: You're kidding.
Dr. Foreman: I'm not breaking into my boss' house.
House: I'm your boss.
Dr. Chase: She's scarier then you are.
House: She's a woman.
Dr. Foreman: You really want to screw Whitey? Be one of the few black men to live long enough to collect social security. Take the medicine.
House: You see the world as it is, and you see the world as it could be. What you don't see is what everybody else sees. The giant gaping chasm in between.
Dr. Cuddy: House, I'm not naive. I realize...
House: If you did, you wouldn't have hired me.
House: This isn't about race. Unless "annoying" is a race.
(asking if House has slept with Dr. Cuddy)
Dr. Chase: You two are just too nasty to each other not to have been...nasty.
House: Hey, I can be a jerk to people I haven't slept with. I am that good.
(about Cuddy's bed)
House: This is where it all happens!
Dr. Cuddy: Thank you very much. This guy's been working for me for a long time...
House: Do I get bonus points if I act like I care?
Music: The song sung to Alfredo by his mother, Luisa, before his surgery, is called "Duérmete, Mi Niño" and was sung by Christine Avila (the actress who played Luisa), recorded specifically for the show.
The song featured at the end of this episode was Damien Rice's "Delicate."
At the end there is a blurb assuring the audience the American Humane Association monitored the cockfighting to make sure no animals were harmed.
Sela Ward is billed as Special Guest Star.
House: Take the Scooby Gang and spread out.
This is an allusion to the children's cartoon, Scooby-Doo, where a group of young adults investigate mysteries, and solve puzzles.
House: Snap, Crackle, and Pop. You got some Rice Krispy in there.
Rice Krispies is a cereal that make a popping sound when you pour milk over them.
The title refers to the nursery rhyme:
Humpty Dumpty sat on a wall; Humpty Dumpty had a great fall; And all the king's horses; And all the king's men; Couldn't put Humpty together again
The episode's patient becomes ill after falling from a roof; presumably, House and his team are the king's men, but they do succeed in "putting Humpty together again". Mostly.
House: Friday's child heads to the kidneys.
Referencing the old children's poem: Monday's child is fair of face, Tuesday's child is full of grace, Wednesday's child is full of woe, Thursday's child has far to go, Friday's child is loving and giving, Saturday's child works for its living, And a child that's born on the Sabbath day, Is fair and wise and good and gay.
Patient: I didn't fill that Oreo's prescription.
"Oreo" is a derogatory term for African-Americans who are supposedly black on the outside and white on the inside.