At a swim meet, a 12-year old diver, Mary, goes onto the board and makes her dive, but when she comes up one of the bystanders has collapsed. At Cameron's apartment, House pays a visit to ask her back but she refuses. Before they can get into it further, House is paged – there's an outbreak at the clinic. He returns to find the place crowded with patients and doctors – Cuddy suspect meningitis at the pool center and dragoons him into service. Mary has a rash and a sore neck, and her parents are out of town. House suspects something and brings Foreman to look at her and Chase to do research. They give her a lumbar puncture but when Foreman returns she's been moved and when he finds her, he tells her the tests prove negative, but she begins bleeding at the mouth.
Chase and Foreman run a probe into her intestinal tract to look for lesions but they find nothing. While House and Chase spar over Chase's duties, and Cuddy spars with House over the fact they're understaffed due to Vogler leaving with his money, a camera in her stomach shows a suspicious swelling. Cuddy interrupts to tell them to show up for the 3:00 interview for Cameron's replacement – it doesn't go well for the interviewee. Foreman tries to get a sterile room for Mary for a bone marrow extract and ends up in the morgue, but she goes into arrest.
As her seizures increase, House and his staff consider their options and try a transcanial ultrasound. House has another applicant who is quickly dismissed despite her ability to deal with House. The transcranial shows Mary is bleeding into her brain and needs emergency surgery, which Cuddy arranges. The surgery relieves the pressure but they still don't know the cause. House concludes from her rash that she's bleeding into the skin and that . . . she's pregnant. A TTP condition is messing up her body and causing the symptoms. They'll have to clean her blood and terminate the pregnancy, but Mary doesn't want her parents to know and the law permits it. House can't give the parents a straight answer but after the operation Mary tells her parents what happened.
With the next applicant, House informs her the position has been filled. He goes back to Cameron who refuses to come back . . . unless they have dinner and a date. House agrees.