Hugh Laurie shows British phrasing, despite a nearly flawless American accent. House says, "Tomato sauce," with the emphasis on "sauce," as a Brit would, opposed to American with an emphasis on "tomato."
The students are seen taking the AP Calculus exam. Later, when Cameron is looking for poison in the garage, she is wearing a long coat and gloves. The AP Calculus exam is only given (nationwide) in May - too warm to be wearing a coat and gloves in New Jersey.
Dr. Cameron: Are there any stronger treatments for the organophosphate poisoning?
House: Oh, damn it, you caught me. We went with the weak stuff. Just trying to save a little money.
House: You're brain damaged. Doomed to feeling good for the rest of your life.
House: I want you to go to his house and find his stash. I'll bet you know all the good hiding spots.
Dr. Foreman: Actually, I never did drugs.
House: (speaking to Cameron) Better go with him. In case he gets high.
Dr. Wilson: (quoting a poem from a patient of House's) "The healer with his magic powers! / I could rub his gentle brow for hours. / His manly chest, his stubbled jaw, / Everything about him leave me raw..."
House: Psych ward's upstairs
Dr. Wilson: "...with joy. Oh, House, your very name / Will never leave this girl the same." It's not bad for an 82-year-old. She asked me to give that to her true love.
House: What can I say? Chicks with no teeth turn me on.
Dr. Wilson: That's fairly disgusting.
House: And that's ageism.
Dr. Wilson: You better watch yourself around this babe.
House: Well, you're getting good at this God-like doctor racket. Why don't you talk her out of this lunacy?
Dr. Foreman: She's not really a big fan of mine.
Dr. Chase: Or mine.
House: Well, only one male left in the bullpen, and he throws like a girl.
Dr. Cameron: I hate sports metaphors.
Dr. Cameron: You really never did any drugs?
Dr. Foreman: Now this is gonna be a racial thing.
Dr. Cameron: Deflecting a personal question with a joke. Gee, who do I know that does that?
Dr. Foreman: Yeah, I'm just like him. Except for the angry, bitter, pompous, cripple part.
Dr. Cameron: Maybe we should all pitch in and get you a nice cane. You already have the matching gym shoes.
Dr. Cameron: I'll check into it.
Dr. Foreman: I'll make the call.
Dr. Chase: I'll keep the kid alive. For a while at least.
House: I'll have lunch.
Georgia: I notice colors more. And music. I...I'm really hearing music. I'm eighty-two, and I'm supposed to be playing canasta with the other old ladies, but…now when I see a guy with a cute butt...I just can't stop looking at him. (looks at House) Or a sexy beard.
House: And you figure that enjoying cute butts is a sign of disease?
House: I am extremely disappointed. I send you out for exciting new designer drugs and you come back with tomato sauce.
Dr. Foreman: The kid was just taking his AP calculus exam when all of a sudden he got nauseous and disoriented.
House: That's the way calculus presents.
House: I assume "minimal at best" is your stiff upper lip British way of saying "no chance in hell"?
Dr. Chase: I'm Australian.
House: You put the Queen on your money. You're British.
Matt: Who are those guys?
Margo: Oh, they're the arrogant jerks that saved your life.
House: Although there's a real good chance...
Margo: What? Matt might kick off?
House: It's a little blunt. I was going to say "run out of time." Just kinda let my voice trail off...
Margo: What makes you think you're right this time?
House: The same thing as last time.
Dr. Wilson: Hey, I'm a man - I don't have time for laundry. I'm saving lives here!
House: I'm sorry - the fact that the sexual pleasure center of your cerebral cortex has been overstimulated by spirochetes is a poor basis for a relationship. I learned that one the hard way.
House: Would you step outside for a minute, Mr. Adams?
House: Because you irritate me.
Margo: Who are you?
House: I'm the doctor who's trying to save your son. You're the mom who's letting him die. Clarification-–it's a beautiful thing.
Dr. Cuddy: (to House) Her only sign of mental illness is that she disagrees with you. Some would consider that a sign of sanity.
House: But I am going to admit (Georgia) to the hospital for tests.
Mark: What tests? She's just old.
House: And you're just insufferable.
Georgia: And now...I think about Ashton (Kutcher) all the time. (whispers) All the time.
Georgia: You remind me of him. Same bedroom eyes.
House: People are always mixing us up.
Dr. Foreman: You know why House thinks I'm a druggie?
Dr. Cameron: This is going to be a racial thing, isn't it?
Mrs. Miller mentions that she can't stop thinking about Ashton Kutcher. John Patrick Amedori, who plays Matt Davis in this episode, also played a young Ashton Kutcher in the 2004 movie The Butterfly Effect.
Hugh Laurie and the crew seem to be having fun going on about Chase's purportedly English accent. Jesse Spencer is actually Australian, while Hugh Laurie has an English accent that he covers up to play House.
In 2005, when this episode first aired, FOX made American Idol the lead-in to House in hopes of getting higher ratings. Former lead-in The Rebel Billionaire had lower ratings than House. The promos played up the similarities between House and Simon Cowell.
Dr. Wilson: Godot would be faster.
Godot is an allusion to the title of Beckett's most famous work, Waiting for Godot. Beckett uses the characters' interaction to symbolize the tedium and meaninglessness of modern life, both major themes of the existentialists.