House

House: Just think of it as one giant rack for mankind. In this description of would-be astronaut Greta's breast enhancement surgery, House is referring to Neil Armstrong's famous statement as he became the first person to step on the moon, "That's one small step for [a] man, one giant leap for mankind."

House: I never opened for Springsteen or slept with Barbara Feldon In the 1960s, Barbara Feldon played the very attractive Agent 99 on the TV show Get Smart.

House: Two down, Kitty Carlisle. Referencing the actress who was a recurring guest panelist on the game show What's My Line?. John Charles Daly, the moderator, would count the questions that the panelists used up, by saying "one down," "two down," etc., then going on to the next panelist.

House: Heeeerrreee's Osama! Referencing The Tonight Show Starring Johnny Carson, and Ed McMahon's traditional greeting as Carson came onstage.

Dr. Wilson: No, but since she's not a dead cat it's scientifically impossible for her to be in two places at once. Referring to the thought experiment by Erwin Schrödinger, often called "Schrödinger's Cat", in which he says a cat placed in a sealed box (unobservable), with a fatal device which has an unknown, random probability of going off after an unknown, random amount of time, cannot be said to be dead or alive -- its condition is truly indeterminate, hence it is actually in both states at once, until you decide open the box to take a look, and "fix" the state/condition it is in. This ties in closely with Heisenberg's Uncertainty Principle and a device called a Josephson Junction.

House: Would you pull an ass out of a pit on the Sabbath? Referencing Luke 14:5, when Jesus challenges the Pharisees when they question whether he should heal a man on the Sabbath.

Title Referencing the 1979 book by Tom Wolfe, detailing the American space race starting in the late 1950s. The book was made into a movie in 1983 starring Ed Harris, Scott Glenn, and Sam Shepard.