Reference-When I.R. Baboon sticks banana peels in I.M. Weasel's Rocket and then proceeding to blow up, it is in slight reference to the Challengerexplosion that happened exactly 11 years, 6 months and 6 days from the episode's first airing.
Goof: Despite saying the mission was set at night, it is actually the afternoon as the sky was blue.
The Queen of Yurp's scepter is a plunger.
This is the first time the Kingdom of Yurp is seen.
In this episode, when Weasel is seen without his fur, he looks like a little human with a big weasel nose and a tail. However, in later episodes when Weasel strips of his fur, he looks like his normal weasel-like shape but without the fur.
Baboon gets married in this episode, yet in the next episode he isn't anymore.
We learn that Baboon has a sister named Barbie.
When Weasel and Baboon have their brains switched, their voices change as well. Rather than merely swapping voice actors, Charlie Adler continues to voice I.R. Baboon, but doing an imitation of I.M. Weasel's voice. Additionally, Michael Dorn imitates I.R. Baboon's voice when voicing Weasel with Baboon's brain.
The reason Weasel and Baboon ended up with the others brain is because the doctors that operated on them were ignorant and believed that the size of their had matched the size of their brains.
At the beginning Cow is in the same retirement of the cartoon stars but when I.R. decides to go to the retirement you see Cow beside him.
How come Weasel, I.R., and Loulabelle weren't freezing in the snow since they weren't wearing coats?
Just how did I.R. manage to stick that tieny-whieny fishing-hook inside an icecube?
There are no pictures in the picture frames when the camera zooms out and we see Weasel fat.
When Weasel tells Cow that he has to go back for Baboon, his neck was thin. But when he says, 'I going to need your help.' his neck is huge!
This episode is consider controversial because bestiality was consider a taboo during the Hays Office Code, such as the actual ending of "Red Hot Riding Hood" (1943), which was destroyed due to the appearance of half wolf children and replaced with a suicidal wolf scene for TV.
Weasel and I.R. pronounced Conchita in such a racy animal nature as "KunCheetah". On the Spanish audio version, the name is pronounced regularly as "Coan-chit-a", the actual pronunciation since it's Spanish.
This is the only episode when Weasel is married to a woman with bestial children.
The kid calls Baboon "Fat Head" the entire episode.
The Red Guy loses two of his teeth banging on the table, but they disappear from the table in the next shot.
Baboon doesn't know what a "gladiator" is, but accepts to become one just because it has the word "glad" in it.
Actually, the word "gladiator" comes from the Latin "gladius", meaning "sword".