With the help of Artemis and the gang, Charlie attempts to put together a musical based on the song, "Nightman." However, his friends each have their own ideas on how to present it.
To get Paddy's pub labeled a historical landmark, the gang tells the Philadelphia Historical Society that their bar was responsible for cracking the Liberty Bell.
After discovering Dennis' erotic memoir, Mac and Frank attempt to make some money off of it. Meanwhile, Dee and Charlie decide to spend a day in each other's shoes.
With the help of Mac and Dennis, Frank and Charlie attempt to figure out who pooped in their bed. Dee leads Artemis and the Waitress on a ladies night out on the town.
Charlie wants Mac to beat up the Waitress's new boyfriend, but what he doesn't know is that his friend is the one who's seeing her. A hurt Dennis tries to convince Charlie that he is the true best friend after the title was bestowed to Mac.
After Frank invests in a billboard, he and Mac attempt to find Paddy's next top model. Dennis enters the competition to prove that he has what it takes to be featured on the billboard. Meanwhile, Charlie and Dee work together to come up with the next big thing on Youtube.
To capitalize on the high gas prices, the guys invest in barrels of gasoline that they plan to sell door to door. Meanwhile, Dee and Frank resort to some drastic measures to stop Bruce Mathis from donating Barbara's money to a Muslim cultural center.
After Charlie and Dee unknowingly eat some of Frank's human meat, the two develop an insatiable hunger for it. Meanwhile, Mac and Dennis get into sport hunting and go after what some might consider to be the most dangerous animal in the world.