Why after staging the crash do the police only have two people following Murchison - Frank and John? If they had blanketed the area with undercover surveillance operatives Murchison couldn't have gotten away so easily.
Where did John get balloon animals from? That's not the kind of thing you just carry with you or have on hand.
After Frank and John plays basketball, John forgets the jacket he took off earlier.
Frank: Hey, you wouldn't happen to know how many little bumps there are on a basketball.
John: Yeah. And they're not bumps, they're pebbles. 122 per square inch.
Frank: If the two of you say "sulphur" together again, I'm going to hurt somebody.
Frank: (to John) You know, you'one to talk about difficulty with social interaction.
John Doe uses the skull of someone to reconstruct what the person's face would look like. MacGyver, with whom this show is often compared to, uses this same method in episode 4.1 - "The Secret of Parker House".
Sprague Grayden as Karen doesn't appear in this episode.
Frank: What are you now – Dr. Phil with hair?
Referencing the talk-show psychologist Dr. Phil, with his own program as of 2002, The Dr. Phil Show.