When MacGyver drives away from the cemetery, he puts his sunglasses on as the car starts. Then, his glasses are gone, and he puts them on a second time.
MacGyver picking the lock with the lightbulb filaments has been confirmed as possible by the Mythbusters.
When MacGyver finds Brian's car he reaches in the window to take the keys. When Sara comes back for the car the windows are up.
The bartender during the sequence where MacGyver talks with a one-armed doctor switches sides of the bar between camera angles.
The computer MacGyver copies files from—as well as the table it rests on—switch between shots.
When Kate shuts off power to the building, she types the command in to the computer "close all circuits" when in fact it should be "open all circuits". Closing a circuit means to complete a circuit so that power flows and open means to cut a circuit so that power doesn't flow.
MacGyver's horse's saddle flip-flops color throughout the episode.
MacGyver catches a shotgun cartridge in his right hand. Then the angle changes and he's holding it in his left hand.
When Pete shows Charlie and MacGyver the location of the Victoria to Typhoon Harry, the silhouette of the storm is more reminiscent of a tornado rather than a tropical cyclone.
When moving from the balcony to his apartment's interior, MacGyver's shirt changes color.
Despite the dozens of failsafes and backups that any nuclear plant in the U.S. has, a couple of bullet shots not only cause the reactor to go into meltdown, but damage the safety controls intended to stop the meltdown.
Amy explains that they'll die several minutes before the sludge get to the waste disposal chamber, because of the extreme heat that precedes it. However, they exit from the chamber and the sludge pours in immediately as soon as they leave.
When Quayle is flipping through the security cameras he looks at the room where Mrs. Chong and Pete are. Pete disappears and then reappears when he flips back to the room again.
The alarm reset button is on the top of the clock, but is later on the bottom.
Pete is shot in his left arm; however, later he is shown with his right arm in a sling.
MacGyver has an aversion to guns, but despite the fact they knock three of Axminster's armed mercenaries out, Harry never takes any of their guns. He's clearly comfortable using guns: there are several mounted on the walls when MacGyver first arrives at the cabin.
After his men are defeated, Axminister has a rifle but climbs up onto a porch and jumps on MacGyver. Then he knocks MacGyver down from surprise. Then he unslings the rifle from his back. Finally he prepares to shoot MacGyver. Fortunately for MacGyver, Axminister forgets that he can shoot from ambush.
Another episode early in the series where MacGyver's complete aversion to guns isn't established: in the opening gambit he casually threatens two enemy agents with their own gun.
When MacGyver is cutting the tree branch, he's sitting on the branch cutting with one hand. In the next shot, he's standing behind the branch using both hands.
In syndication, the phone number Harry gives MacGyver is cut short by two numbers. On the DVD, the phone number is intact.