After a one season hiatus, the "You are now watching MADtv" theme song returns as the show's opening theme song, albeit in a different form.
Johnny Gan: How many Angelina Jolies does it take to do me nice and sloppy? Only one.
When Johnny Gan talks about potential replacements for Jay Leno, he mentions Carson Daly, Conan O'Brian, and David Letterman. In reality though, he holds up pictures of the late Johnny Carson, the 1982 film character of Conan the Barbarian, and off again/on again Van Halen lead singer David Lee Roth respectively.