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Final episode in which Michael McDonald is a castmember, who with 3 episodes as a featured player, 226 episodes (231 counting the season 6 holdovers) and 10 seasons as a star, is officially MADtv's longest staying castmember in the show's history.
Final episode in which Jordan Peele is a castmember.
Debra Wilson, Mo Collins, and Michael McDonald are the only three people to have all appeared in some way, shape or form in The 100th Episode, The 200th Episode, and The 300th Episode while Michael McDonald is the only person to have been a castmember during all of those episodes.
For some reason, the dance music that is usually played in The Sopranos P.A.X. T.V. Presentation when the stripper is on-screen didn't play in this episode.