First episode that makes reference on why Mannix quit from Intertect:
Mannix While talking to Jody (whose Deaf)
" Well one day I got fed up and I, uh, cussed at the machine.
I think I heard it cuss back, so I quit."
The second season introduction of Mannix, uses footage from the episode "To The Swiftest, Death".
This is the first appearance of Gail Fisher as Peggy Fair, Mannix new assistant.
Joe Mannix's ride was a dark green 1968 Dodge Dart GT convertible.
First episode that deals with sign language and is played by real life deaf actress Audree Norton.
In the second season, Paramount Pictures is the studio handling the show, after Desilu. The automobiles are now furnished by Chrysler.