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Coulson and their team must deal with a traitor within and an organization that distrusts them.
Coulson and his team--what's left of it--go all-out to stop HYDRA. Meanwhile, Fitz and Simmons try to escape a watery grave, and Grant begins to question Garrett's sanity.
Coulson and his team prepare to destroy the Kree city, but learn where Whitehall and his people are drilling in and go to take them on. Meanwhile, Skye meets her father for the first time, and he reveals his plan to get revenge on Whitehall for killing Skye's mother.
Coulson leads an assault on the captured helicarrier, taking Cal along with them. Meanwhile, Jiaying prepares to unleash the Terrigen crystals on the world, and Skye is forced to confront her mother.
Garrett and Triplett return to help track down the Clairvoyant, who sends Deathlok to stop them.
Agent Maria Hill returns to help Coulson as what's left of S.H.I.E.L.D. collapses due to the efforts of HYDRA.
Coulson's team goes undercover against HYDRA to learn their true plans... and Grant's connection to them.
While Coulson's team tries to track down the secret, they meet the Doctor. Meanwhile, Bobbi interrogates Sunil and Ward kidnaps his older brother.
Jemma tells Fitz about what happened to her on the alien planet... and the man who helped her survive.
The life of Coulson's true love is threatened by HYDRA and the team has to undertake a perilous mission to save her. Meanwhile, Grant tries to get close to Skye and convince her to decrypt the hard drive, but discovers that there's an unexpected complication.
Col. Glenn Talbot pursues Coulson's team as they begin to uncover S.H.I.E.L.D.'s darkest secrets.
Coulson realizes that Jiaying intends to set off a war, but tries to avoid launching a counter attack for fear of hurting Skye. Meanwhile, Skye appeals to Jiaying to reconsider, and Grant tries to give Kara closure.
As Coulson tries to save Skye, he teams up with Ward's former SO, John Garrett.
Coulson and Gonzales are forced to join forces with an unreliable ally to defeat Hydra.
Coulson and his team take on Hive before he can set off the warhead and transform the world's population into his Inhuman slaves. However, one team member will sacrifice themselves to stop the Inhuman leader.
An undercover Jemma finds herself the subject of a security crackdown by Hydra's security chief, Bobbi Morse. Meanwhile, Raina tries to negotiate with Coulson to get the obelisk before Whitehall has her killed.
Coulson and his team go undercover aboard a train to try and get a lead on the Clairvoyant.
Hive's master plan is completely revealed, forcing S.H.I.E.L.D. into action.
Jemma puts her cover as a researcher for Hydra at risk to stop her new organization from acquiring Donnie Gill, a Gifted who could prove valuable to both sides. Meanwhile, Fitz confronts Grant for the first time since Grant tried to kill him.
Talbot demands that Coulson register the S.H.I.E.L.D. Inhumans, and is less than thrilled to learn about the threat of Hive. Meanwhile, Daisy helps Lincoln to escape the base so that he can join her.
Coulson and half of the team head to San Juan to enter the Kree city, while the other half go to Vancouver to keep Raina from falling into Hydra's hands. However, Grant is one step ahead of them.
Someone is killing people and leaving the alien writing etched on the corpses. As Coulson's team pursues the murderer, they discover a connection to their director's past.
Hydra impersonates S.H.I.E.L.D. and launches an attack on the UN to turn the world against Coulson and his people. As they rush to find the source of Hydra's new weapons, Coulson negotiates with the American Senator spearheaading the efforts to destroy S.H.I.E.L.D.: Grant's older brother Christian.
While a S.H.I.E.L.D. strike team goes after Hive, Mack tries to rescue Daisy before it's too late. Meanwhile, Fitz and Jemma create an anti-toxin against Hive's parasites, and Lincoln insists on testing it on himself.
Skye must make a decision about her powers, while Coulson finds himself going up against... S.H.I.E.L.D.
While Skye questions her future with the Inhumans, Melinda must decide her future in the war between the two sides of S.H.I.E.L.D.
While their teammates investigate a problem at S.H.I.E.L.D. Academy, Coulson and Melinda turn up unexpected information about Skye's parents.
Fitzsimmons tries to find a way to stop Hive as he continues to recruit Inhumans to his side.
Coulson and his team go underground to continue the fight against Hydra. Besides dealing with the American government's attempts to capture them, the team must track down a World War II artifact of amazing power.
Centipede's interrogation of Coulson helps him uncover information about his death and mysterious resurrection... but at the potential cost of a teammate's life.
Daisy and her team of Inhumans rescue Coulson and his people from Hydra. However, they soon learn that despite their apparent success, a traitor within the team threatens to tear S.H.I.E.L.D. apart from the inside.
Coulson and Melinda go undercover to obtain a painting that may hold the answers to Coulson's attacks. Meanwhile, Fitz fights his own problem to help the team when the Bus is sabotaged, while Whitehall forces Raina to bring him the obelisk.
While Jemma secures the Kree city, Skye is put into quarantine. Meanwhile the team carries out an operation against Hydra to eliminate the people who arranged Trip's death.
While Coulson and his team try to stop Hydra from getting the obelisk from Creel, Talbot continues his pursuit of the fugitives. Meanwhile, Mack reaches out to Fitz, while Lance must consider his future after he loses his friends.
On the alien planet, Coulson hunts down Grant to get revenge for Rosalind's death. Meanwhile on Earth, the team secure the portal in the hopes of bringing their comrades home.
While Coulson's team infiltrate the ATCU base, Coulson interrogates Rosalind about what they discover during the break-in. Meanwhile, Gideon explains to Grant the true origins of Hydra.
Coulson accompanies Rosalind to the ATCU facility, while Daisy, Mack, and Lance run surveillance on Banks. Meanwhile, Melinda takes Bobbi with her to track down the man who attacked Andrew.
Coulson swears to do whatever it takes to bring in Grant, after the rogue agent strikes at someone close to Coulson. Meanwhile, Gideon captures Jemma and Fitz, and Mack convinces Joey and Lincoln to join the new team of Inhumans.
While Skye meets a fellow "Inhuman," Coulson takes on Gonzales for the future of S.H.I.E.L.D.
Coulson and Lance turn to Grant for help. Meanwhile, Skye and Lincoln become involved in the inter-S.H.I.E.L.D. struggles.
While Fitz helps Jemma recover the information from her phone that could help the team open the portal, Coulson and Rosalind join forces to track down Andrew after Lincoln comes in out of the cold to confirm that Andrew is Lash.
When Lorelei goes after the male members of the team, the female members get an assist from a god: Lady Sif of Asgard.
Tensions rise between S.H.I.E.L.D. and the Inhumans, with Skye caught in the middle. Meanwhile, Coulson reveals what he's been doing with the missing millions.
After a battle, Lady Sif finds herself on Earth with amnesia, and turns to S.H.I.E.L.D. for help. Meanwhile, Bobbi and Mack continue their own operation within the team, risking exposure.
While Fitz tries to get Jemma back, Coulson and Skye discover that another organization is also hunting Inhumans.
The team turns to Elliott for help figuring out where the monolith took Jemma, and he leads them to a castle in Gloucestershire. Meanwhile, Lance prepares to hunt down Grant and turns to Melinda for help.
Daisy gets a terrifying glimpse into the future and S.H.I.E.L.D. tries to prove her vision isn't set in stone.
To expose S.H.I.E.L.D.'s supposed crimes to the world, Cal gathers a team of "super-villains" and lures Coulson back to his hometown. Meanwhile, Melinda brings in her ex-husband to help evaluate Skye's psychological condition after her recent transformation.
While Coulson and Rosalind launch their first joint operation to find Lash, Melinda worries that Lance is too invested in his attempts to kill Grant.
In the aftermath of the Dark Elves' assault on Earth, Coulson and his team are called in to pick up the pieces... and find an artifact that may kill one of them.
Coulson recruits a former enemy, Mike Peterson, to help the team take on Centipede, but they soon find themselves under threat from an unexpected quarter.
Coulson and President Ellis come to an arrangement, and Coulson begins the hunt for Malick. Meanwhile, Daisy leads a team to Bogota to track down a rogue Inhuman, and discovers that there's more involved than they first thought.
The team goes up against a killer who leaves their victims' bodies floating in mid-air.
The team deals with the revelation of Skye's altered nature, while Bobbi and Mack tell Lance where their true allegiance lie. Meanwhile, Grant and Agent 33 go on a personal mission.
President Ellis sponsors an international symposium on the Inhuman problem, and Coulson and Talbot must attend it. Along the way, they try to find Malick's inside man. Meanwhile, a foe from the past makes a return, and the team find a potential vaccine against Terrigenesis.
Grant and Fitz are sent on a suicide mission, and Coulson desperately works to save their lives from within S.H.I.E.L.D.
Bobbi and Hunter follow Gideon to a compound in Russia, and discover what he has in mind for the Inhumans in Russia.
Gideon wrestles with his past as Hive calls a meaning of Hydra's inner council. Meanwhile, Daisy and Lincoln look for a former Afterlifer with information on Hive, while the others investigate Hydra's newest business acquisition.
Melinda is forced to confront her past when a mysterious force threatens the team.
The team travels to Asia to track down a girl in a flowered dress who holds the key to locating a young man with a dangerous power. Meanwhile, Skye's loyalties are divided between the team and Rising Tide.
Coulson and the team go after a mysterious master thief, only to discover that she has connections to Coulson that could ruin his life.
While Mack and Daisy try to get to Lincoln before the ACTU does, Lance and Melinda try to get close to Grant. Meanwhile, Fitz nurses Jemma back to health after her rescue.
A new group, the Watchdogs, go public and destroy an ATCU facility as they declare on the war on the Inhumans and the ATCU. Meanwhile, Mack tries to spend some downtime with his brother.
In the aftermath of the Avengers' battle in New York City, the world attempts to come to grips with the presence of superheroes, gods, and aliens in their midst. Agent Coulson is resurrected under mysterious circumstances and forms an elite team of agents from SHIELD to keep track of a secret organization known as The Rising Tide. Meanwhile, they must deal with other menaces, such as a man who suddenly finds himself with vast uncontrollable power.moreless
It's a race against the clock when Skye leads the team to find Dr. Franklin Hall, who has been abducted by unknown kidnappers.
Coulson and his team travel to Peru to recover a mysterious artifact designated 0-8-4. However, they run up against an enemy agent, Camilla Reyes, who also wants the item.