The pages composing the girl's face on the cover of the DVD contain a hint to the plot, as they are the lines that are narrated by the narrator Emma Thompson in the movie "Stranger Than Fiction", when Will Ferrell's character Harold Crick brushes his teeth in the morning.
This episode was probably meant to air at a future date, or is at least set a few months into the future, as the DMG rejection letter seen under the opening credits is dated February 29, 2007. Interestingly enough, there is no 29th day in February of 2007.
When Rob Hanisee arrives at the guesthouse he is assigned room 217. This alludes to the room in the novel written by Stephen King where the ghost of an old lady is in the bath. (The director of this episode, Mick Garris and Stephen King are close friends)
The Twilight Zone (1959)
The line "...there's a signpost up ahead, you've entered the Twilight Zone." is an allusion to the anthology series.