Melissa and Joey-
An upgrade of "Who's the Boss". While the cliches were out in full force, the undeniable fact is that Melissa Joan Hart and Joey Lawrence play off each other very well. Plus there is that whole 90's nostalgia thing its got going for it.
In fact-everything else in the show is extraneous to the two main leads. They are the best part of the show.
I'm not sure how long the novelty factor can be kept up. The show does have a chance of succeeding. It was stupid and funny; its entertaining enough, even though the canned laughter was annoying.