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The Atlanta Falcons (12-2) travel to Ford Field to face the Detroit Lions (4-10).
FInal Score: Atlanta 31 Detroit 18
The New York Jets (6-7) travel to LP Field in Nashville to face the Tennessee Titans (4-9).
Final Score: New York 10 Tennessee 14
The Houston Texans (11-1) travel to Gillette Stadium in Foxborough, Massachusetts to face the New England Patriots (9-3).
Final Score: Houston 14 New England 42
The New York Giants (7-4) travel to FedEx Field in Landover, Maryland to face the Washington Redskins (5-6).
Final Score: New York 16 Washington 17
The Carolina Panthers (2-8) travel to Lincoln Financial Field to face the Philadelphia Eagles (3-7).
Final Score: Carolina 30 Philadelphia 22
The Chicago Bears (7-2-0) travel to Candlestick Park to face the San Francisco 49ers (6-2-1).
Final Score: Chicago 7 San Francisco 32
The Kansas City Chiefs (1-7) travel to Heinz Field to face the Pittsburgh Steelers (5-3).
Final Score: Kansas City 13 Pittsburgh 16 (OT)
The Philadelphia Eagles (3-4) travel to the Louisiana Superdome to face the New Orleans Saints (2-5).
Final Score: Philadelphia 13 New Orleans 28
The San Francisco 49ers (5-2) travel to University of Phoenix Stadium to face the Arizona Cardinals (4-3).
Final Score: San Francisco 24 Arizona 3
The Detroit Lions (2-3) travel to Soldier Field to face the Chicago Bears (4-1).
Final Score: Detroit 7 Chicago 13
AFC West rivals the Denver Broncos (2-3) and San Diego Chargers (3-2) meet from Qualcomm Stadium in San Diego.
Final Score: Denver 35 San Diego 24
The Houston Texans (4-0) travel to MetLife Stadium in East Rutherford, New Jersey to face the New York Jets (2-2).
Final Score: Houston 23 New York 17
The Chicago Bears (2-1) travel to Cowboys Stadium to face the Dallas Cowboys (2-1).
Final Score: Chicago 34 Dallas 18
The Green Bay Packers (1-1) travel to CenturyLink Field to face the Seattle Seahawks (1-1).
Final Score: Green Bay 12 Seattle 14
The Denver Broncos (1-0) travel to the Georgia Dome to face the Atlanta Falcons (1-0).
Final Score: Denver 21 Atlanta 27
The San Diego Chargers travel to O.co Coliseum to face the Oakland Raiders in an AFC West game.
Final Score: San Diego 22 Oakland 14
The Cincinnati Bengals travel to M&T Bank Stadium to face their division rival the Baltimore Ravens.
Final Score: Cincinnati 13 Baltimore 44