Or how do you want it to end? Obviously, Monk solves Trudy's murder and the christmas gift he never opened is either a massive clue as to who killed her (which might mean Trudy knew she was going to be killed, and didn't tell Monk) or he will open it after solving her murder, which will show Monk is finally past the death of Trudy, and can move on (Mr. Monk is on the Run showed how Monk was not beyond it, because of how he kept imagining Trudy's car being blown up over and over again). I would find it very interesting if Monk ended similar to Six Feet Under, showing how all of the characters end up, and eventually die. I have a feeling Randy would die doing something incredibly dumb, as his intelligence has declined in the past few seasons.
I guess the series finale will start out with a case, probably a car bomb or something similar, they determine it is the same type that killed Trudy (or someone tries to kill Monk with the same type of bomb, possibly on Trudy's birthday or some important day in Monk's life) about 20-30 minutes into the ep, then Monk goes over all of the clues, tries to solve this murder so he can solve the murder of Trudy, then once he solves it, his phobias slowly decrease in severity, because the death of his wife and his inability to solve caused his phobias to intensify in the first place.
Basically Monk will be happy for the first time, and probably stop dwelling on his past.
