"Murphy Brown" is one of the best-written sitcoms ever. Over the course of 10 seasons, the show had many plot twists, some of which were unusal for a sitcom. For example, in the 10th season, Murphy is diagnosed with breast cancer. Though cancer is certainly a sensitive subject, somehow the show manages to find humor in it. Other major events on the show are Murphy's pregnancy and the birth of her son Avery. "Birth 101," the episode in which Avery makes his entrance, is undoubtedly one of the funniest. Throughout all the changes in cast and plot line, there's always one thing a viewer can count on, Murphy's endless parade of secretaries. Almost any sort of unusual or offbeat person one could think of showed up as a secretary at some point.