It is revealed in this episode that Kerry has empathy for Adam Lyon concerning what he has to go through at Charles Darwin Middle School.
It seems that Jake Spidermonkey has gotten over his jealousy in Kerry to Dance? of Kerry being attracted to Adam when Jake was also attracted to Adam; as Jake was willing to help re-train Adam to be civilized again so that Kerry would have a good date at her debutante ball.
It is revealed that prior to this episode, Adam had been pulling all-nighters for three weeks straight in order to pass his mid-terms. And that's what caused him to act weird. It also explains why Adam briefly acted weird in A Mid Semester Life's Dream. He was already feeling the effects of insomnia. So all the events between A Mid Semester Life's Dream and Human Behavior took place within three weeks. Glazed and Confused only took one entire week.
Revealed weaknesses (that were cured later) of characters:
Jake Spidermonkey: Had poor eyesight.
Windsor T. Gorilla: Was afraid of puppies.
Lupe Toucan: Is overdependent on her vulture boyfriend, Corey. Virgil "Bull" Sharkowski: Turns into a Bull Moose Shark on every Wednesday. Adam Lyon: Sounded too much like a girl. Ingrid Giraffe: Her weakness to everything was her weakness.
Slips Python: Has feelings (left unchanged.)
Third time that Slips has appeared naked in an episode.
It's learned in this episode that Adam has at least one uncle, and this one uncle is an Optometrist who lives in the same city that Adam lives in.
Running gags in this episode: 1. In Human Behavior, Adam Lyon keeps acting like different animals. 2. Jake and his friends keep spraying Adam with water bottles whenever he does something wrong. 3. Jake is not able to see clearly without glasses or corrective surgery. 4. Creatures continue to shun Jake by ignoring him.
Billboard gags: 1. Human Behavior: The Midterms are A. Today? (Checkmarked) B. Tomorrow? (Blank) C. None of the Above? (Blank) 2. Four Eyed Jake: Join the Repelican Party.
Lupe Toucan: I totally don't need you Corey, now fan harder!
This is the first time that Adam Lyon has ever returned Ingrid Giraffe's affection for him (albeit accidentally.)
The fourth wall is broken in this episode after Miss Chameleon tells Adam Lyon that he is perfect for voicing cartoons. Slips asks Windsor: "What's a cartoon?" And Windsor responds: "You're in one."
Second appearance of Lupe's vulture boyfriend, Corey.
Magilla Gorilla: The name of the store Feebles Pet Shop is a refernce/parody of Peeble's Pet Shop which appeared on the popular 1960's Hanna-Barbera cartoon.