Kristin Gunther begins to suffer from great anxiety, confusion, and seizure-like movements. At first, doctors believe she simply has a viral form of meningitis, but after Kristin returns home, she becomes extremely anxious and delusional. Also, she loses her ability to breathe on her own, and her heart rate becomes dangerously low. All of this turns out be caused by an autoimmune disease called Anti-NMDA receptor encephalitis due to a teratoma in her ovary. Food deliveryman Mark Chernek suddenly develops strange symptoms affecting his feet. He has pressure that soon disappears, pain, reddish splotches, fluctuating temperatures, and bluish discoloration that spreads from his toes to his ankles, which cause him to eventually give up on his job. Mark realizes that he has an autoimmune disease that affects blood vessels of the hands and feet called Buerger's disease, which is caused by his heavy smoking habit.moreless
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