Kabuto spilled blood all over Tsunade and it totally freaked her out. Kabuto took advantage and sends Tsunade flying. Naruto asked Jiraiya why Kabuto attacked Tsunade and he explained that Kabuto is Orochimaru's subordinate.
Jiraiya orders Shizune to fight Kabuto and he will fight Orochimaru. But before they start he asked her to do something about his body and she tells her that the effects of the drugs will last for a while and that she can't do anything about it. Then Naruto asks him what he should do and Jiraiya tells him to protect Tsunade and the pig. Naruto gets mad and he tries to do Kage Bunshin no Jutsu but Jiraiya tells him that its meaningless to do that. Then the fight starts. Both Jiraiya and Orochimaru(with the help of Kabuto)used a Summoning Jutsu. Orochimaru summons a giant snake but Jiraiya can only summon a small toad. Shizune then says that Jiraiya cannot fully mold his chakra because of the drugs and that is why he can't do the Summoning Jutsu properly. Orochimaru was able to see that Jiraiya is handicapped instantly. Kabuto explained to him that Tsunade gave Jiraiya a drug so that she could use Jiraiya as a sacrifice. Naruto gets mad that they made fun of Jiraiya so he too used the Summoning Jutsu. He too failed in his attempt to summon Gamabunta. Orochimaru starts his attacks. Shizune saves Tsunade but was attacked by Kabuto. Naruto flies around but was eaten by the snake. Orochimaru attacks Jiraiya but was stopped when Jiraiya used Doton: Yami Numa (Earth element: Hell swamp). Shizune and Kabuto fights and Kabuto hits Shizune right in the heart. Shizune counters using Ninpou Dokugiri (Poison mist). Kabuto got away and attacked Shizune by coming out of the ground. Naruto gets away from the snake. Orochimaru starts to attack Jiraiya but he uses Ninpou Hari Jizou (Needle guardian) to stop him. The defense fails and Orochimaru bites Jiraiya. Shizune lost to Kabuto, Naruto is down so Kabuto heads for Tsunade. Tsunade is still freaked out from the blood so she couldn't defend herself. Then Orochimaru talks about that Naruto doesn't have any talent and that the only way to become a great ninja is to learn all the jutsus. Jiraiya tells him that he is wrong. He says that it's not the number of jutsus you know but to have the guts to never give up. Meanwhile, Kabuto is about to hit Tsunade in the head but Naruto blocks his punch using his head. Naruto used the Rasengan but Kabuto used his technique and hits Naruto in the leg. He tells Naruto to give up and run away. Meanwhile, Tsunade is having flashbacks about a kid dying and also a man. Kabuto heads for Naruto and beats him up. Naruto stopped one of Kabuto's kicks and pushed him back. He stood up but was knocked down again when Kabuto hits him in the face. Naruto stands up again and tells Tsunade that he will take that unlucky necklace that she wagered on their bet. Kabuto gets mad that he stood up again and starts his attack while Naruto creates a clone. Tsunade tells him to run but he refused. Kabuto hits Naruto using a kunai. Naruto held on to Kabuto's arm and using the clone he starts to create the Rasengan. He was able to create it and hits Kabuto right in the chest.