If you guys look through naruto shippuden manga series. We know that a sharrigan and rinnegan is needed to defeat the ten tailed beast and sorry i forgot how to spell its name. So Naruto and Sasuke will not die for awhile. Naruto will become 6th hokage near the end of the series. Will Tsunade die and stand down who can say. Sasuke will return to the village as a konaha ninja after the war. Well thats it for now bye.