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In Dickens' original book, Oliver is the boy who visits Fagin in jail, not the Artful Dodger as in this adaptation.
In Dicken's original book, Sikes is running from pursuers over rooftops and accidentally hangs himself while attempting to climb down. In this adaptation, Sikes hides in the sewers and hangs himself intentionally as either a remorseful gesture or to escape the haunting by Nancy's ghost.
In Dicken's original book, it is Oliver's nemesis Noah Claypole who spies on Nancy and tells Fagin of her meeting with Brownlow and Rose. In this adaptation, it is the Artful Dodger who tells Fagin.
In Dickens' original book, the wounded Oliver is left by Sikes and taken in by the Maylie family whose house Sikes attempted to rob. Rose Maylie cares for Oliver and she is not the ward of Mr. Brownlow as indicated by this adaptation.
This production is the first time that a biracial or black actress (Sophie Okonedo) has portrayed Nancy in a TV series or film.