Brain: Come on Pinky, be a man! Like Elanor Roosevelt!
This cartoon was first aired as part of episode 18. The gag credit for this episode is: Caruncle - The membrane that lines the abdominal cavity.
The tiger papa dying in the last film Pinky watched before the world domination plan is a refrence to The Lion King.
The title of this episode Brain's Song is an allusion to the 1971 movie Brian's Song, which is the story of a football player with terminal cancer.