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At Eddie's wedding, Hank helps a theater legend who's experiencing confusion and memory loss; and he reconciles Eddie and Evan before the ceremony. In other events, Paige and Evan await the results of a pregnancy test.
Hank meets a woman who worries that she has an inherited disease; Eddie makes a medical decision without consulting Hank; and Jeremiah learns that Boris went to clinical trials without his input.
Hank treats an overworked Keller; Divya meets Hank's mentor, but he's changed due to a medical issue; Evan and Paige struggle with the demands of IVF; and Jeremiah makes a video for Divya's baby shower.
In the series' 100th episode, Hank works in the ER for the first time in years and has difficulty following Evan's orders during a quarantine situation that involves Jill. In other events, Jeremiah bonds with a patient; and Divya worries about Lena.
Hank finds romance while in Hong Kong trying to prevent the theft of Boris' medical records; Divya treats a repo man whose target is a airplane and a yacht; and Paige convinces Evan to rethink their parenting path.
Evan deals with a cyber-attack on Hamptons Heritage when Diana's hacked records go viral; Divya helps Jeremiah and his parents with family issues; and Hank and Jen go on a date.
In the Season 8 premiere, Hank treats a politician; Divya's future hits a roadblock; Jeremiah returns, but struggles with his first patient; and Eddie has a surprise that doesn't elicit the expected reactions from Hank and Evan.