In the Seann William Scott episode, Jarret said that he was repeating his junior year, but in this episode, he says he's finally going to be a sophomore after four years.
Carson Daly (hosting Last Call): Hi I'm Carson Daly, and I'm a massive tool.
Jared Fogel: If you lose weight, you can beat those terrorists!
George W. Bush: Do I get to talk to anyone with the name Smith or Jones or Cooper or Knievel?
This episode features the last DeMarco Brothers sketch.
During the monologue, Horatio Sanz (dressed up as Spiderman) throws up despite the fact that Kirsten told a stagehand to get Horatio a bucket to vomit in (the stagehand misses his cue). NBC and E! reruns have a dress rehearsal version where this doesn't happen.
This is Will Ferrell's last appearance as George W. Bush. The role of Bush would go to three different actors over the course of the next two seasons.
Obie Trice is NOT in this episode. Many people think he was there and that he said his name at the end of "Without Me", but it was actually Proof saying, "Free Obie Trice" (because he was in prison at the time). Eminem even said Proof's name twice -- once during the performance, and once during the "DeMarco Family Dancers" sketch.