This is the only episode in the series so far where all 4 of the main boys use the F-word in the same episode.
Although Justin Bieber is a Canadian, he does not have floppy heads or beady eyes like all other Canadians in the series.
Captain Hindsight does not appear in this conclusion.
Kenny gets reborn from his mother just like the time way back in Cartman Joins NAMBLA.
In the Coon's second comic book, a picture showing the Coon and Cthulhu destroying a synagogue was reused from the previous episode, Mysterion Rises.
This episode ties with Pinkeye from Season 1 for the most number of Kenny deaths with 3 times.
Cartman: F***ing Mint-Berry F***ing Crunch.
Cartman's use of the "cute kitten" technique on Cthulhu mimics the behavior of the kitten in the classic Merrie Melodies short "Feed the Kitty."