The Broflovski family is getting ready for a big occasion: Kyle's little brother Ike is about to have his Bris. Everything is going fine until Stan discovers just what a 'Bris' is: they're going to cut off Ike's penis Kyle, thinking his parents have gone insane, vows to protect his little brother by hiding him away where they can't get him. Meanwhile, Mr. Mackey gets fired from his job when an anti-drug demonstration goes wrong.
This episode is pivotal as it isn't really about Cartman, Stan, Kyle or Kenny but rather Mr. Mackey and Ike and it shows that other characters can hold up an episode just as well as the four main boys can. Even though both of the plots are flawed when it comes to originality and laughs as both of them deal with uneasy topics like drugs and circumcision; both of them contain some fun moments at erratic occasions.
Even though the episode looks much unsophisticated with the usually cut and paste look to it; it's what's on the inside that matters. Trey Parker steals the show as Mr. Mackey and expands his range with emotions like depression and hallucinating. Isaac Hayes delivers a memorable cameo as Chef. Ike's Wee Wee is an example of the show's not so classy beginning but its excellent overall.