The Black Widow is one those foes who doesn't actually pose a threat to Space Ghost but rather controls henchmen and a monster who does. Early in the episode when Space Ghost is ensnared by the spider webs shot at his hands, and Space Ghost's struggling grunts as he can't reach his power bands are classic.
This is the first episode in the series where Space Ghost is forcibly stripped of his power bands. (Which begs the question, how did she do it? But that's a question only over-analyzing fans like me would dare to ask!)
True to form, Space Ghost dispatches the Black Widow's boss monster in heroic style; Space Ghost and the twins leave with the Black Widow vowing revenge. This episode left me feeling like she could actually come back later and possibly do Space Ghost some real harm.