"Doctor Worm" may be a reference to the They Might Be Giants song of the same name.
Space Ghost: A shark on whiskey is mighty risky. But a shark on beer is a beer engineer!
Space Ghost: This is Old Kentucky Shark! He has been here!
Space Ghost: Ah yes, my documentary... I made this for public television but they told me it was stupid and grossly inaccurate.
Space Ghost: Bears and sharks always travel together. Just look at them, walking through the wooded forest, paw and fin. It's on account of their teeth that makes them "natures best friends".
Willie (to shark): Hey, how you doin' Tex?
Zorak: Hey, that bear's a yankee.
Willie: Well F*$@ him!
Zorak: Oh, so NOW there's a liquor store involved.
Space Ghost: Crack a window open, will ya? Hahaha...
Space Ghost's Space Cowboy Song: "Some people call me the Space Cowboy... Dumb people haul trash around..."
This episode began life as a "lost" episode of Space Ghost, which was pulled from production when the writers wanted to make a new series out of it. See the entry for Baffler Meal for more details.
This is the first appearance of what would become the Aqua Teen Hunger Force, here called the Baffler Meal.