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Spider-Man must battle his own teacher when New York State University science professor Dr. Curt Conners is transformed into a monstrous lizard creature as a side effect of an experiment that allows lost limbs to grow back.
Robbie has set Peter up with a job interview with a researcher by the name of Dr. Mariah Crawford. However, when he gets to her lab, he finds her under attack by a monstrous man who deems himself Kraven the Hunter. Threatening Spider-Man by kidnapping Robbie, can Spider-Man rescue Robbie while fighting this beast of a man?moreless
The Kingpin is furious at Spidey and sends the Shocker and later the Rhino out to finish him off with the aid of another new invention of Alistair Smythe. Meanwhile, Eddie Brock, as the symbiote creature Venom, is busy playing cat and mouse with Spider-Man, intruding on Peter's private life and making it clear he knows the web-slinger's secret identity. Peter soon realizes that the pumped-up Eddie as Venom is stronger than he is. Worse than that: Spidey's spider-sense doesn't work around him!moreless