In this episode a Krabby Patty is in the safe while in other episodes the actual written formula is in the safe.
Goof: As the motorcycle gang circles Squidward, none of the jackets is missing an "M".
When the motorcycle gang first pass Squidward, two of their jackets actually say "The Mile Ones".
Why did Pearl talk back to Mr. Krabs? Why didn't Mr. Krabs punish her?
Who in the right mind would sell drinks that are made out of toxic?
If Squidward says that they haven't sold any soda in days, wouldn't they have already noticed there was another store everyone was going to, especially the one in front of the Krusty Krab restaurant?
How can a lawn mower shred SpongeBob and Patrick in small pieces?
"Born to be Wild" is often being played along with "Best Day Ever."
In other episodes, the pet is called a worm. In "Best Frenemies," it is called a dog.
The German title for "Born to be Wild" is: "Getragen, wild zu sein."
In previous episodes of the series, the Krusty Krab once carried Kelp Shakes.
Apparently, anyone who drank Kelp Shakes would would gradually get green hair, but Plankton and Mr. Krabs immediately got covered in green hair compared to the almost 24 hours it took everyone else in town.
The Kelp Shake buildings divide like bacteria and seem contagious.
There were three Kelp Shakes next to the Krusty Krab, two on the left and one on the right, but when SpongeBob was talking to Mr. Krabs and Plankton, two of the Kelp Shakes on the left were gone.
Patrick's Goofy Goober underwear can be seen.
German title: "Beste Fr-einde."
Kelp Shakes caused the drinker to become hairy and have light green kelp all over their body.
Jill Talley's name at the end credits is misspelled as Jill Taliey.
Mr. Krabs: Come back here, you little booger!
SpongeBob: So, you wanna join our biker gang?
Squidward: No, I do not.
Patrick: How about our biker club?
SpongeBob: How about our biker organization?
Squidward: No! I don't wanna join your biker alliance, your outfit, or your fellowship!
SpongeBob: Hmm... how about our coalition?
Mr. Krabs: Alright, from now on, NO DRINKS FROM THE OUTSIDE ARE PERMITTED!!!!!!!
(all the customers leave while sipping their kelp shakes)
Mr. Krabs: I bet that Plankton's behind this. (walks around to the back of the Kelp Shake store and finds Plankton) AH-HA! I knew that you were behind this!!
Fish: Why, they're the most ferocious, bloodthirsty biker gang under the sea. They've destroyed entire cities in an afternoon. (laughs maniacally then jumps back into the hole he was digging)
SpongeBob: Bloodthirsty bikers? And they're headed straight for Bikini Bottom. I've got to warn everybody. I better take the shortcut. (as the next scene of bubbles comes up, so does SpongeBob. Bubble pops in the Krusty Krab) Mr. Krabs!
Mr. Krabs: (gasps) No, it's impossible. I must've counted me money a dozen times, and it still comes up short. Profits are down. Oh, I feel sorry for me self. (walks out of office)
Squidward: Would you like a drink with that order?
Customer: Oh no, thanks. I got me one of those new kelpshakes before I came in here.
Squidward: That comes out to two dollars even.
Customer: Wow, what a steal.
Scooter: Yeah, I feel protected now.
SpongeBob: Patrick, it`s working.
Patrick: I`m drinking blood. Do you want some?
SpongeBob: Oh, no, Patrick. I`m drinking diet blood.
SpongeBob: Do I look tough?
Patrick: I wouldn`t mess with ya.
SpongeBob: Neither would I.
Exterminator #1: It will take years to clean this up.
Exterminator #2: I sure feel sorry for anyone who drank this.
Plankton: Oh, yeah!
Karen: Oh, no.
Karen: I wouldn't do that if I were you. There's another ingredient that-
Mr. Krabs: Hey, I paid good money for this. Of course I'm gonna drink it.
(drinks the kelp shake)
Mr. Krabs: Waa! I don't get what the big deal is. This tastes like a wet gym sock.
Plankton: Really? Let me try.
(SpongeBob runs screaming)
SpongeBob: They shut down the Kelpshake restaurant! (runs away screaming)
Farmer: Don't you know who the wild ones are?
SpongeBob: No, and I don't know who you are, either.
Patrick: Those bikers think they`re so tough, with their leather hats, and leather pants!
SpongeBob: And their leather socks!
Patrick: If we dressed like that, then we'd be the big, scary bikers and they'd be... little baby doody-heads.
SpongeBob: Say that again, Patrick.
Patrick: Little baby doody-heads?
SpongeBob: No, no, not that part, the part about dressing up like big, scary bikers.
SpongeBob: Patrick! There's a ravenous gang of bikers!
(Patrick doesn't pay attention)
SpongeBob: Patrick! Didn't you hear me?
Patrick: I heard you. But what I didn't hear was a hello.
SpongeBob: (annoyed) Hello, Patrick.
Patrick: Hello, SpongeBob. (pauses) AHH! BIKERS! AHH! Run for your life! (runs)
Mr. Krabs: Wouldn't you like to spend some money?
Biker: Wouldn't you like to kiss the seat of my pants? (walks away angrily)
Mr. Krabs: Wait! No! Come back!
SpongeBob: Where is Squidward?
(camera shifts to Squidward on a motorcycle)
Squidward: Ride to live and live to ride!!!
Until "The Slumber Party," Pearl did not appear in any other episodes because the girl who played her was busy working on another series.
Sandy and Gary do not appear in this episode.
The bubbles that SpongeBob used as a shortcut are the bubbles that are always changing the episodes to another scene.
Pearl makes a cameo appearance in "Best Frenemies."
Plankton doesn't appear in "Born to Be Wild".
Patrick doesn't appear in "Best Frenemies".
This is the first time Mr. Krabs has interacted with Karen.
When SpongeBob takes the "shortcut," he breaks the "Fourth Wall" by running into an invisible wall.
This is the second appearance of the analyzer, the first was in "Plankton!"
Patrick and SpongeBob drink blood and "diet" blood.
Old Man Jenkins is one of The Mild Ones.
This episode aired during the 2007 Kids Choice Awards pre-show.
This episode aired in Germany and the U.K. before the U.S.
This is the eleventh time Plankton has tried to steal the Krabby Patty formula in the series.
This is the second appearance of the Guard Worm. The first was in "The Lost Mattress."
The title sounds like a combination of best friends and worst enemies.
Mr. Krabs actually gives Plankton a Krabby Patty in this episode. But chases him afterwards.
The Wild One (1953) is a movie about two motorcycle gangs that take over and terrorize a town.
Drinks: Blood and Diet Blood
This is maybe a parody of the drinks Coca-Cola and Diet Coca-Cola.
The hat SpongeBob wears looks like the duck's hat from The Grim Adventures of Billy and Mandy.
When SpongeBob and Patrick are dressing up as bikers, you can hear a part of the hit 1958 song "Rebel Rouser" by Duane Eddy.
Born to be Wild
The title itself is the name of a Steppenwolf song of the same name.
The helmets that The Wild Ones wear are the same helmets worn by the Germans in World War I.
When SpongeBob, Mr. Krabs, and Plankton grew green hair, they resembled the Grinch from Dr. Seuss's books.
The Kelp Shake stores are literally on every street corner, which is clearly a reference to the overabundance of Starbucks locations.
Kelp Shakes are a parody of alcoholic drinks. They taste bitter at first, but then get really addictive.