This is sort of a remake of second season's "Rules of Acquisition", but with a better script and a better performance from the lead guest star. Taking place largely on Ferenginar (in its Star Trek debut) this women's liberation story is an improvement because the issue is more personal to Quark and explored in greater depth.
Like the best Ferengi episodes, the script simultaneously celebrates the culture (likely the only one where sons are uncomfortable with their mothers wearing clothes) and pokes fun at it ("that will be three slips of gold-pressed latinum for the use of the chair") while never letting the overall story get lost in the shuffle. Armin Shimerman (Quark) and Max Grodenchik (Rom) get the bulk of the scenes, and it's clear that by this point in the series the two know just how to work together and love doing it. They're joined by guest star Andrea Martin (Mom) who finds a niche in the family for her character and demonstrates that Mom loves each of her boys in different ways and knows just how to handle them. Sadly, there's no appearance from Wallace Shawn as Grand Nagus Zek, but this opens the door for Liquidator Brunt, the first of three recurring Star Trek characters played by the fantastic Jeffrey Combs. Director Auberjonois pulls all their performances together so well, their dialogue carries the show and most viewers won't even notice that the entire episode includes only about six minutes of music.
The B story is a mini sequel to the previous episode, following up on Sisko's promise to meet a pretty freighter captain. There's not much to it (and what there is resembles the first half of TNG's "Lessons") but it's a nice building block for the future of the show.
All that said, "Family Business" doesn't stand out from the crowd. There are better Ferengi episodes, and nothing happens here that's too important or memorable.