Nitpick: Admiral Janeway says there is nothing in the Alpha Quadrant but exit aperture. However, on the map seen just a moment ago, it appears there IS a hub in the Alpha Quadrant. In addition, it is odd that the Borg never used this in their attempts to invade Earth.
Trivia: The last line of the finale is identical to the last line in the pilot episode, "Caretaker".
Trivia: Seven Of Nine states that there are only six transwarp hubs in the entire galaxy. Yet later, when she is in the Astrometrics Lab showing Janeway(s) and Chakotay the hubs, only four are shown.
Chakotay: Nobody can guarantee what's going to happen tomorrow, not even an Admiral from the future.
The Doctor: (as B'Elanna groans from labor pains) Try to relax, Lieutenant.
B'Elanna: Oh, if you tell me to relax one more time, I'm going to rip your holographic head off!
The Doctor: I hope you don't intend to kiss your baby with that mouth!
Janeway: You know what? I shouldn't be listening to details about the future.
Admiral Janeway: Oh, the almighty Temporal Prime Directive. Take my advice - it's less of a headache if you just ignore it.
The Doctor: I wouldn't celebrate yet. Klingon labor can sometimes go on for days. (B'Elanna screams loudly) Of course, I'm sure that won't be the case here!
Kim: Maybe it's not the destination that matters. Maybe it's the journey. And if that journey takes a little longer, so we can do something we all believe in, I can't think of any place I'd rather be, or any people I'd rather be with.
Paris: (Raises coffee mug) To the Journey!
Borg Queen: You've infected us with a neuorolithic pathogen.
Admiral Janeway: Just enough to bring chaos to order...
Admiral Janeway: What about the Temporal Prime Directive?
Janeway: To Hell with it!
Janeway: (last line) Set a course... for home.
Admiral Janeway: (To the Borg Queen) I don't know how you do it. All those voices talking at once - you must get terrible headaches.
This was the last Star Trek episode to be produced in standard definition. The entire series of Enterprise would be shot in widescreen for high-definition broadcast.
Originally aired, together with part one, as a two-hour finale.
Tarik Ergin (Lt./Ensign Ayala) is the only actor, besides the regulars, to appear in both this episode and the pilot, "Caretaker".
Kate Mulgrew (Captain Kathryn Janeway), Robert Beltran (Lt. Commander Chakotay), Tim Russ (Lt. Commander Tuvok) and Robert Duncan McNeill (Ens. Tom Paris) are the only actors to appear in every episode of the series.
After the series ended, the soundstage for Star Trek: Voyager was destroyed along with the former Star Trek: Next Generation sets that were transferred to Star Trek: Voyager after Star Trek: The Next Gereration ended.
Nominated for two 2001 Emmy awards in the categories "Outstanding Special Visual Effects for a Series" and "Outstanding Music Composition for a Series (Dramatic Underscore)".