Nitpick: Lt. Tuvok mistakenly wears Lt. Commander pips.
Nitpick: When the wormhole is first discovered by Ensign Kim, he states that it is "virtually microscopic" and in the next sentence states that the aperture is thirty centimetres in diameter. Thirty centimetres is approximately one foot, which is far from microscopic.
Nitpick: Janeway and Tuvok discuss that there is a one in four chance that the wormhole could lead to the Alpha Quadrant. This is based on the assumption that the wormhole leads to one of the four by the four quadrants in the galaxy. However, there is no reason to discount the possibility that it could lead to any number of infinite locations elsewhere in the universe.
The Doctor: If there's one thing you can count on, it's that I am the last to be told about anything that happens on this ship.
The Doctor: Let's just say I've become accustomed to being treated like a hypospray.
Telek R'Mor: If you should find your way back during my lifetime I'd be an old man, but I would welcome a message from you. I am Telek R'Mor, of the Romulan Astrophysics Academy.
Janeway: I promise you'll hear from us, because we will get back.
(talking to Telek R'Mor)
Janeway: We have no way of communicating with Starfleet, with our friends and families. We're hoping you might be able to relay a message for us. Our crew is not large. Each of them could write a short personal message. You'd be welcome to read them all before passing them on. I think you'd be convinced that they're nothing more than the heartfelt words of some very lonely people.
(Talking about the Doctor)
Kes: I don't understand why people treat him the way they do.
Janeway: How do people treat him?
Kes: As though he doesn't exist. They talk about him while he's standing right there. They ignore him, they insult him.
Janeway: Well, as a matter of fact, I've been hearing the other side of the coin. Many of the crew have complained that the Doctor is brusque, even rude, that he lacks any bedside manner. We've been talking about reprogramming him.
Kes: You can do that? It doesn't seem right.
Janeway: Kes, he's only a hologram.
Kes: He's your medical officer. He's alive.
Janeway: No, he's not.
Kes: He's self-aware, he's communicative, he has the ability to learn.
Janeway: Because he's programmed to do that.
Kes: So, because he's a hologram, he doesn't have to be treated with respect or any consideration at all?
(talking to Kes)
Baxter: If I had to get treatment for something serious, if I needed surgery for instance, would he be performing it?
The Doctor: Of course. And quite expertly too.
Baxter: I don't know. I'd have to think twice about that.
The Doctor: Fine, and if you were lucky you wouldn't die on the table while you were making up your mind.
Janeway: You don't have the luxury of thinking of yourself as an Emergency Medical Program anymore. You've become a full-fledged member of the crew.
With so few sets and new characters being used in the episode, it was intended to a bottle show. Unfortunately, this did not reduce the stress for everyone, since the script had to be rewritten to a new four act format, and no one got the final draft of the script until after they had gone home for the day, giving them less time to prepare for the shoot.
They had originally planned to introduce Janeway's gothic holonovel in the teaser of this episode, but they decided that they would shelf that idea and use Kim's discovery of the wormhole instead, since it was more exciting and integral to the plot. The holonovel would later be introduced in the episode "Cathexis".
The Dark Matters trilogy in the Voyager book series was inspired by the events in this episode.
Although credited, Ethan Phillips (Neelix) does not appear in this episode.