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Sam and Dean investigate an angel slaughter and discover that Castiel is already looking into the matter. The individual responsible captures Castiel, while Dean wonders whether ti's time to tell Sam the truth about Ezekiel.
When four members of the same church chastity group disappear, Sheriff Jody Mills calls in Sam and Dean for help. However, Dean soon disappears and Sam and Jody have to go after him.
A man named Sonny calls Dean for help, and Sam is surprised to learn that Sonny and Dean spent time together at a home for delinquent boys. Sonny needs help dealing with a ghost and the Winchesters agree to help investigate. Meanwhile, Dean links up with an old girlfriend from his time in the home.moreless
When Castiel calls the Winchesters about mysterious disappearances in his neighborhood, Dean is forced to keep Sam (and Ezekiel) away from Castiel by asking to help Kevin and Crowley decipher the tablet. Meanwhile, Crowley asks for one phone call to Hell in return for his cooperation.
To solve two murders, Dean casts a spell to bond with the German Shepherd that witnessed both crimes. However, the spell has an... unfortunate side effect.
The Winchesters call Charlie in to help them with a Men of Letters computer, only to discover a magical green-webbed wall that leads to the land of Oz. Now the trio must join forces with Dorothy to stop the Wicked Witch from traveling to the real world and wrecking havoc.
Ezekiel warns the Winchesters that a group of disgruntled former angels are hunting their friend Castiel, and the brothers set out to find him before it's too late. Meanwhile, Castiel learns more about the human lifestyle.
Dean has a surprise for Sam and Kevin: Crowley, locked up in the trunk of the Impala. While they try to track down the demons on Earth, Abaddon continues with her plan to rule Hell.
Dean is devastated by the fact that the doctor tells him Sam won't make it, so he promises any angel willing to help that he will owe them a favor. Many angry angels want to find Dean and kill him, but Ezekiel gets to him first. At the same time, Sam is fighting for his life, and Castiel has a hard time surviving without his powers.moreless