The Men of Letters ask Mary to perform a special mission for them, which involves her recruiting Sam, Dean, and Castiel without their knowledge of who she now works for. The mission soon goes south and Castiel is mortally wounded.moreless
When Dean starts losing his memories of everything, Sam turns to Rowena for help.
Sam and Dean travel with Castiel to help him investigate the murder of several angels that he worked with when he was a warrior angel. They soon discover that a woman is seeking vengeance and will stop at nothing to kill Castiel and his remaining assoicates.moreless
Sam and Dean must find a way to escape the black site where the government has imprisoned them. Meanwhile, Castiel and Samantha find themselves at loose ends with no idea where the brothers are or if they're even alive.moreless
Sam and Dean try to trap Lucifer, but discover that he's found a near-perfect hiding place: the President of the United States.
Lucifer plans to use his host body, Vince Vincente, to gather an army of fans and bend them to his will. Sam, Dean, Castiel, and Crowley try to track him down and stop him before it's too late.moreless
Sam and Dean attend the wake of a Hunter, Asa Fox, who got his start in the business after Mary saved his life. After Mary arrives, the Winchesters soon discover that one of the other Hunters is a killer.moreless
Nazi necromancers attempts to bring back Hitler's spirit from the pocket watch that it's trapped in, and only the Winchesters can stop them.
Sam and Dean investigate two mysterious deaths that suggest demons were responsible. The trail leads them to a devout religious family that harbor a dark secret.
The sounds of a crying baby lure victims into an abandoned house, and Mary suggests that they investigate the case. Meanwhile, Crowley and Castiel team up to track down Lucifer, who is forcing Rowena to help him preserve his host body.moreless
Lucifer takes over the body of a rock star. Meanwhile, Dean, Castiel and Mary try to rescue Sam, but Dean is uncomfortable with putting Mary in danger, even though she insists on going along.moreless
Dean is reunited with Mary and Castiel, and they search for the missing Sam... unaware that the Men of Letters are torturing him for information on the American Hunters. Meanwhile, Crowley searches for Lucifer, who is leaving a trail of burned-out bodies in his wake as he jumps from person to person.moreless
With the fate of the universe in their hands, Sam, Dean, Castiel, Crowley, and Rowena come up with a desperate plan to kill Amara. However, one of them must sacrifice their existence to do so.moreless
The Winchesters ally with Chuck and Lucifer to destroy Amara, but discover that they need an even greater force to weaken her enough so that Chuck can strike the final blow.
God finally meets with the Winchesters, but he's not what they expected. Meanwhile, Amara requests a meeting with Dean, and the Winchesters set out to rescue Lucifer so that he can help God reimprison God's sister.moreless
Sam and Dean travel to a town in Colorado where a fog is spreading the same madness that they ran into when they first encountered Amara. Meanwhile, Metatron is summoned to a meeting with God.moreless
The Winchesters team up with two other hunters to take on the chitters, cicada spirits who possess humans so that they can reproduce.
While the Castiel-possessing Lucifer tries to take control of Heaven, Sam and Dean hear out Crowley on his plan to stop Amara.
Sam and Dean take on a pair of werewolves... and one of them manages to kill Sam. When Dean gets back to civilization, he kills himself in a desperate attempt to ge a Reaper's attention and make a deal to bring Sam back to life.moreless
The new owners of a house accidentally break a seal, unleashing a creature that Bobby and Rufus trapped several years ago. Now Sam and Dean are working the same case, and have to save a new wave of coma victims before their bodies wither and die.moreless
Sam and Dean decide to take a break and check out a wrestling tour. However, when a wrestler turns up dead, the brothers suspect demonic influence. Meanwhile, Crowley escapes from Hell with a little help from a friend and seeks out a weapon to kill Lucifer.moreless
Sam locates an artifact capable of destroying Amara... that was lost at sea in 1943. The brothers convince Castiel--secretly Lucifer--to transport Dean back in time to recover the artifact.
A babysitter turns up dead on Valentine's Day, her heart ripped out, and the Winchesters soon discover that she was the victim of an Aramiac curse.
Sam and Dean meet with Jody and the two girls that she's housing: Alex and Claire. Claire has asked the brothers to help her investigate a series of recent disappearances, but Jody insists that there's nothing to them.moreless
The Winchesters investigate two deaths at a retirement home, where the victims bashed their skulls in because of an intolerable screeching noise. They soon discover that the deaths are connected two deaths that occurred in Ireland 30 years ago. Meanwhile, Lucifer explores the world that he's been reborn into.moreless
While Lucifer tries to convince Sam to let him out of the cage, Dean and Crowley come up with a plan to seal the Devil away permanently. Meanwhile, Castiel joins forces with another angel to confirm if Amara is dead or not.moreless
While Dean tries to find Amara, Sam and Crowley convince Rowena to help them summon Lucifer from the cage so that Sam can try and persuade the Prince of Darkness to help them seal the Darkness away once more.moreless
Sam is forced to relive his childhood when his imaginary friend Sully appears... and asks him to help solve the murder of another imaginary friend.
Sam and Dean team up with Sheriff Donna to stop a ghostly killer who possesses people who wear costumes.