When Dean and Sam are in the mill they hear a sound coming from the locker room. As Sam opens the locker a cat comes jumping out making Dean scream like a little girl. Just before the scene ends you see Dean and Sam leave the frame with Dean laughing.
In the scene when Sam and Dean are invited into the sheriff's office, for the first time. Sam gets out of his chair and begins adjusting his shirt collar. But when the shot changes his hands are down to his side.
For some reason the closed caption says that Waylon Jenning's Slow Rollin' Low is playing in the police station when Dean and Sam go into the sheriff's office. No such music is playing.
Autopsies are suppose to be recorded when doing the procedure. The doctor did not record himself, instead he was talking with Sam and Dean.
Dean: (referring to the gun) I'm not carrying that. It could go off. I'll man the flashlight.
Sam: You do that.
Dean: But why me? Why not you? I mean you got hit with the spleen juice.
Sam: Yeah, uh, you see Bobby and I have a theory about that too. Turns out all three victims shared a certain…personality type. Fred was a bully, the other two victims, one was a vice principal the other was a bouncer.
Sam: Basically they were all dicks.
Dean: So you're saying I'm a dick?
Sam: No, no, no it's not just that. All three victims used fear as a weapon. And now this disease is just returning the favor.
Dean: I don't scare people.
Sam: Dean, all we do is scare people.
Dean: Okay, well, then you're a dick too.
Sam: Apparently I'm not.
Sam: How ya feelin'?
Dean: Awesome. It's nice to have my head on the chopping block again, I almost forgot what that feels like. It's friggin delightful.
Coroner: Everyone drops dead sooner or later. That's why I've got job security.
Coroner: Oh, sorry. Spleen juice.
Sheriff Britton: Me and Frank, we were friends. Hell, we were Gamecocks. (Dean snickers) That's our softball team's name.
Sheriff Britton: They're majestic animals.
Sam: It's ghost sickness.
Dean: Ghost sickness?
Dean: God, no.
Dean: I don't even know what that is.
Dean: I mean, come on, we hunt monsters. What the hell?!? I mean, normal people, they see a monster and run. No, no, we search out things that want to kill us. Yeah? Huh? Or eat us! You know who does that? Crazy people! We… are insane. You know, then there's the bad diner food and then the skeevy motel rooms and the truck-stop waitress with the bizarre rash. I mean, who wants this life, Sam? Huh? Seriously? Do you actually like being stuck in a car with me eight hours a day, every single day. I don't think so. I mean, I drive too fast and I listen to the same five albums over and over and over again and, and I sing along and I'm annoying, I know that. And you… you're gassy. You eat half a burrito and you get toxic!
Sam: We've been completely ignoring the biggest clue we have… you.
Dean: I don't want to be a clue.
Sam: Yeah. How you feeling, by the way?
Bobby: You sure, Dean? 'Cause this line of work can get awful scary.
Dean I'm fine. You want to go hunting? I'll hunt. I'll kill anything.
Bobby He's adorable.
Sam: Dude, you're going twenty.
Sam: That's the speed limit.
Dean: What? Safety's a crime now?
Sam: Dude, where are you going? That was our hotel.
Dean: Sam, I'm not gonna make a left-hand turn into oncoming traffic, I'm not suicidal. Did I just say that? That was kinda weird.
The guitar riff playing when Dean encounters the small dog in the middle of the episode is the same guitar riff that was used during "Pilot" when Sam and Dean stumbled on the first crime scene; the only difference is that the pitch is one key higher.
Australia: November 3, 2008 on Channel Ten
Denmark: December 28, 2008 on TV3
UK: February 22, 2009 on ITV2
Sweden: April 19, 2009 on Kanal 5
Norway: April 30, 2009 on FEM
Portugal: May 25, 2009 on AXN
Spain: October 5, 2009 on AXN
Germany: December 7, 2009 on Sky Cinema Hits
Poland: March 19, 2010 on TVN7
New Zealand: March 24, 2010 on TV2
Czech Republic: June 18, 2010 on Prima COOL
Finland: May 17, 2011 on Sub
Slovakia: March 20, 2013 on Markiza
The end shows a small clip of Jensen Ackles dancing and singing to Eye of the Tiger.
Music: Eye of the Tiger (Survivor)
Hutchinson: You're scared of Donny? Don't be, he's a sweetheart. It's Marie you got to look out for. She smells fear.
Donald Clark "Donny" Osmond and Olive Marie Osmond are a brother-sister duo of singers, actors, and television hosts. They also had very successful solo careers and have worked with other members of their show business family.
Hutchinson: Tyler and Perry? Just like Aerosmith!
Steven Tyler and Joe Perry are the lead singer and guitarist, respectively, of Aerosmith, a hard rock band formed in Boston, Massachusetts, in 1970.
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