Well, the Andy Milonakis show is just a random show with random people doing random stuff. None of it makes any sense, and it never uses any thought out comedy, just slap-stick and physical humor.
The good: The show can be funny at some point, and it is great to compare it to other shows, because any other show seems perfect compared to the Andy Milonakis show.
The bad: The skits are some of the worst I've ever seen. Some weren't bad, but it seems like this show was aiming for either the incredibly stupid or crazy. The skits sometimes just leave an akward silence amoung the viewers. Also, some of the characters are so incredibly anoying (Andy being one of them) that I could barely finish watching a couple of episodes in order to write a review.
Whatever you do, do NOT watch this show. It isn't funny, it isn't original, it's just a waste of thirty minutes.