When Sheldon and Leo are exchanging the iPhone while talking to Penny, it clearly shows that they were not making any actual phone calls. The iPhone screen switches off while making a call and pressed against the caller's head, but it remains at the contacts screen.
Penny mentions that a play might be the only chance I actually have to play Anne Frank. Actress Kaley Cuoco previously played a character on another show who played Anne Frank in the 8 Simple Rules season two episode, "The Story of Anne Frank and Skeevy".
Sheldon: Stop. We can't do this. It's not right.
Raj: Sheldon, you have two choices. Either you let him put a bigger hard drive in the TiVo, or you delete stuff before we go out of town.
Sheldon: But once you open the box, you've voided the warranty. The warranty is a sacred covenant we've entered into with the manufacturer. He offers to stand by his equipment, and we in return agree not to violate the integrity of the internal hardware. This little orange sticker is all that stands between us and anarchy.
Sheldon: So I'm thinking, 'You won the Nobel Prize, what, three years ago,' so you must deal with a whole lot of 'what has Smoot done lately?' My thought is, we continue my research as a team. You know, Cooper-Smoot—alphabetical—and when we win the Nobel Prize, you'll be back on top.
Dr. George Smoot: With all due respect, Dr. Cooper, are you on crack?
Raj: Have you seen Slumdog Millionaire?
Summer: Oh, yeah, I loved it.
Raj: It's loosely based on my life.
Leonard: Why don't we just call [Penny], have her go into the apartment, get your flash-drive, and email you the paper?
Sheldon: But the flash-drive is in a lock drawer in my desk.
Sheldon: The key is hidden in my room.
Sheldon: Penny would have to go into my room.
Sheldon: People don't go into my room!
Leonard: I see. Well, it seems once again you are caught between a rock and a crazy place.
Sheldon: I hate when that happens.
Wolowitz: I've actually got a shot at a Terminator.
Raj: Oh, please. When it comes to Terminators, you've got a better shot of scoring with Arnold Schwarzenegger.
Sheldon: (about his grandmother) She calls me moon-pie because I'm nummy-nummy and she could eat me up!
Howard: What would Summer Glau be doing riding the train?
Leonard: Maybe John Connor's aboard, and she's protecting him from an evil Terminator.
Sheldon: Unlikely, that's a television show, Leonard.
This episode's end titles has Chuck Lorre's Vanity Card #243.
The 'sci-fi female appearing as herself' role was originally offered to Battlestar Galactica's Katee Sackhoff, who turned down the role.
The German episode title is "Das Placebo-Bier", meaning "The Near Beer". The French title is "Terminator dans le train", meaning "Terminator on the Train". The Italian title is "Il binario del Terminator", meaning "Terminator Railroad". The Spanish title is "La separación de Terminator", an exact translation. The Mexican title is "Terminator multiplicado por diez", meaning "Terminator Times Ten".
As a fan of the show's often physics-centric humor, Nobel Laureate Dr. George Smoot contacted the show and was subsequently found a role as himself in this episode. Smoot won the Nobel Prize in Physics for his work on the Big Bang Theory of the universe using the Cosmic Background Explorer Satellite.
International Airdates: Latin America: April 14, 2009 on Warner Channel; Australia: September 7, 2009 on Channel 9; Germany; December 5, 2009 on ProSieben; Turkey: December 28, 2009 on CNBC-e; Finland: February 1, 2010 on Sub; Czech Republic: November 18, 2010 on Prima COOL; Slovakia: October 6, 2011 on Markiza