The Closer

Season 1 Episode 5


Aired Monday 9:00 PM Jul 11, 2005 on TNT



  • Notes

    • An important feature of the episode is the use of double-blind, multi-phase drug trials. The phases are designed to test various aspects of the drug: its safety (Phase I), its effectiveness (Phase II) and its benefits and sides effects (Phase III). Use of a double-blind is common in studies where the investigators must evaluate patients taking the drug on subjective criteria and/or gather subjective evidence from patients about the effects of the drug. In these studies, neither the patients nor the investigators know who is taking the actual medication and who is taking a placebo (an inert pill, usually made of sugar.) This allows for unbiased evaluation of the medication. Late in the study, the blind is broken, allowing investigators to compare the outcomes of patients who are and are not taking the medication.