The "Leche" billboard can also be seen in the episode "My Peeps".
Billy's Dad has a mutant foot.
Eris is credited but she never appeared in either episodes! This is one of the many times they credit someone who never appeared or talked! This is also the third time they credit Rachael MacFarlane as doing the voice of someone who never appeared. Before it was Mindy.
When Nergal says, "I was just kidding around", the captions misprint "kidding" as "killing".
The word "Leche" on the billboard shown when Grim mentions it is raining cats dogs and Harolds is the Spanish word for "Milk".
Fred, Daphne, Velma, Shaggy, and Scooby Doo from Scooby Doo, Where Are You? make a cameo apperance In Reap Walking.
Billy's Mom: I would have gotten away if it weren't for the meddling kids! (camera points at the Scooby-Doo gang)
Mandy: No, over here.
Grim: Well, it's like they say. Never trust a guy with electric snakes growing out of his back!
Billy: One of the nice things about Uncle Nergal being gone is there's always toaster pastries in there now.
Billy: Grim, please! Watch your language, there are children present!
Grim: And so remember, kids.
Mandy: Don't be afraid of failure.
Billy: It's what keeps family together.
Grim: (talking about outside) It's raining cats and dogs...and Harolds out there.
Billy: I know just what to make us feel better.
Mandy: If you say chocolate-dipped...
Billy: Chocolate-dipped pickles!
Mandy: That's it, I'm out of here.
Nergal seemed to have gained weight since the last time his skin was ripped off probably out of depression.
This marks the second time someone said the famous Scooby-Doo villain phrase since Nigel Planter and the Chambered Pots of Secrets.
This marks the very first time a "The End" tag is shown at the conclusion of this episode.
Cameos by Scooby Doo and Mystery Inc.
Credits: Nergal goes into the elevator. He forgot his luggage. He tries to grab it with his arms, and suddenly he gets caught between two elevator doors.
1) Billy mentions chocolate-dipped pickles.
2) Every time Nergal reply, "Long time, no smell," Billy farts.
Nergal lost the Crypt of Failure boardgame 599 times. After he returns to his wife and son, he actually won that game the first time.
Nergal's voice changed in this episode.
Episode Title: The Loser from the Earth's Core
This is a parody of the 90s movie, "The Loser from Next Door".
Character Name: Sniffles
This is a reference to one of the Looney Tunes character, who is also a rodent named "Sniffles".
Episode Title: Reap Walking
It is a reference to the saying "sleep walking".
Title: Fister's Home for Weird Made-Up People
It's a spoof of CN's original series, Foster's Home for Imaginary Friends.
Burning Game System:
It resembles an XBOX, which did start housefires when it was first put on the market.
Scooby-Doo in Reap Walking
Scooby-Doo and his friends in Mystery Inc. make a cameo when Billy's Mom says the classic villain line from Scooby-Doo, "I would have gotten away with it if it weren't for those meddling kids!"
The grill on the table that read "George" is probably in reference to the George Foreman Grill.