Thrush agent L.C. Carson uses an Indian reservation as a front for his plan to assemble a hydrogen bomb, and kidnaps the tribe's chief, High Cloud, to ensure cooperation. Solo arranges for the Chief's daughter Charisma to return, but she ends up being kidnapped along with Solo and Illya, who is disguised as an Indian. Solo and Illya, along with a band of young Indian warriors on motorcycles, encircle Carson and his men and try to stop them before its too late.moreless
Solo and Illya try to protect Professor Lillian Stemmler from Thrush after she invents a drug called Plus X, which heightens all the human senses. Unbeknownst to them, she is a Thrush agent herself who at first cooperates willingly, then has second thoughts. But Thrush agent Rollo kidnaps her daughter Leslie and forces her to cooperate. The drug is given to three Thrush agents who will attack a U.S. government plutonium plant using their superior senses, while at the same time the guards will be given a dose of Minus X, which dulls the senses.moreless
Solo uses hillbilly clairvoyant Clemency McGill to counter the efforts of Count Zark, a vampirish Thrush agent who plans to use radioactive bats to jam the world's radar systems from his castle. Solo and Clemency make their way to the castle with Illya, but Zark manages to release the bats.
Lucho Nostra and a group of criminals take over a tiny European country, Ingolstein, because it has no extradition treaty. Prince Frederick is afraid to kick them out, so Solo convinces Princess Vicky to return and do so, only to find that she cannot because the treasury has been replaced with IOUs to Nostra for the prince's gambling debts. Nostra arranges for permanent protection by forcing a marriage between Vicky and one of his henchmen, Artie King, but the two actually do fall in love. King duels Nostra, with the fate of the country riding on the outcome.moreless
Thrush agent Elom tries to kidnap a geologist who has developed an earthquake activating machine, but mistakes debt-ridden salesman Buzz Conway for the scientist. Solo and Illya let Thrush go on thinking Conway is the scientist, while Elom lets his attraction for Thrush agent Narcissus Darling interfere with his judgment. Conway is captured, and Solo and Illya must rescue him and find the machine.moreless
Solo, while searching for a secret map in Nevada, swallows an amnesia capsule just before being captured. Thrush agents Arum Tertunian and Longolius try to revive his memory with a seductive female agent, Mara, while Illya races to find him before he starts to remember.
Illya parachutes out of a plane carrying Thrush code documents, but lands in the desert at an abandoned Foreign Legion post run by Captain Basil Calhoun. Illya is accompanied by a stewardess, Barbara while Solo races to find them before Thrush does.
Illya investigates the mysterious disappearance of cats in Soho, and he and Solo discover that a salon run by Madame De Sala is a front for her plan to develop a rejuvenation process, which De Sala plans to use on the now elderly target of her romantic desires, Sir Norman Swickert. Assisted by Joanna Sweet, a nurse, they end up in the bottom of a wine press. Meanwhile, Thrush agent Jordin plots to obtain the process for Thrush.moreless
With the aid of Dr. Elias Swan, Thrush has developed a strain of deadly bees. Thrush agent Mr. Mozart captures Illya and Tavia Sandor and uses a high-frequency sound machine that threatens to shatter their eardrums to force Illya to take him to U.N.C.L.E. headquarters so he can release the bees. Illya does so, but Mozart is intercepted, and in a battle on a rooftop, is shot and the bees get loose.moreless
Solo and Illya travel to Circe to intercept a drone plane carrying a load of Thrush cash. There, they encounter Thrush agent Colonel Hubris, as well as two local girls who are looking for husbands.
Thrush agent Harry Pendleton is captured and commits "suicide" with a reversible chemical, but his superior, Simon Baldinado, refuses to revive him because he is attracted to Pendleton's girlfriend, Jojo Tyler, Solo gets Jojo to help U.N.C.L.E. retrieve the ion projection machine Baldinado has hidden at the mortuary front for Thrushby feigning affection for Baldinado, who allows his personal plans for Jojo to affect his judgment.moreless
Napoleon and Illya travel to the Caribbean to help Dr. Delgado, who is under a voodoo curse and in a zombie-like trance thanks to the local dictator, El Supremo, and his chief of police, Captain Ramirez. The U.N.C.L.E. agents are assisted by Suzy, an American hairdresser whom El Supremo will not let leave the island. They eventually turn to voodoo queen Mama Lou to turn the tables on him.moreless
Squire G. Emory Partridge returns, having acquired in Alaska a large quantity of Quadrillenium X, a very heavy metal with high magnetic powers which Thrush wants to use to disrupt world communications. Solo and Illya are nearly killed by the local Eskimos, but are saved by the chief's daughter, Murphy. Partridge and his niece Victoria capture them, but they escape only to end up in a tavern brawl.moreless
A top-level U.N.C.L.E. conference is to be held in Switzerland, but a nearby boys' school is actually a Thrush front run by Mother Fear and Dennis Jenks that is training its students to be assassins. Solo is captured by the boys, and, when he refuses to reveal the conference location, is forced to operate the controls of two electric trains so they do not collide with each carrying a vial of deadly nerve gas. Illya and Anna Paola, a social worker who resent children, are also captured. The escape, and arrive at the conference just as the boy's choir is ready to kill Waverly and the others with Thrush rifles from under their robes.moreless
Thrush Eastern in Japan acquires a volcano-activating device, and Solo and Illya, along with Cricket Okasada, a film student, infiltrate a toy store and a karate school to find it. Thrush leader Mr. Kutuzov oversees local Thrush head Harada in the operation, and Solo finds himself fighting for his life against a life-size sword-wielding puppet.moreless
Thrush is so eager to get their hands on a boy genius that they murder the boy's father. But then they have to deal with the boy's madcap aunt.
Illya goes to find Thrush's vaporizing machine, but is captured by Sophie, the headstrong daughter of the local tribal chief, Sulador. In New York, Solo convinces retiring Thrush agent David Lewin that Thrush intends to kill him, and elicits his help. Lewin and Solo are taken to the base in the desert, just as Illya leads the band of nomads, whose confidence he has gained, in an attack on the base.moreless
The "Re-collectors" claim to be trying to locate works of art stolen by the Nazis but all is not as it appears.
Napoleon is given the job of searching for Thrush security records.
U.N.C.L.E. and Thrush agents compete to gain possession of a mind-reading device created by a magician who has been murdered by Thrush.
Illya infiltrates a South American prison camp where THRUSH is storing the "Ultimate Computer."
Mr. Alexander, a megalomaniac industrialist, plans to conquer the world like his namesake, Alexander the Great. After escaping the pit and the pendulum in the tomb, Solo battles a bodybuilder in a gymnasium, while at Alexander's farm in Virginia, Illya is nearly cut in two by various farm implements. He is then wrapped in bandages from head to toe in preparation for being mummified by Prof. Kavon. The UNCLE agents seek to stop Alexander from assassinating the president of an Asian country.moreless
Alexander, a megalomaniac industrialist, plans to conquer the world like his namesake, Alexander the Great, by breaking each of the Ten Commandments along the way. He has his henchman Parviz steal the army's "will gas" to help him do so, and Solo investigates. Solo encounters Tracey Alexander, Alexander's ex-wife, who wants to tag along with Solo to get the money Alexander owes her. The trail leads Solo, Illya, and Tracey to a posh party at Alexander's, where Solo defeats their host in a human chess game; to a tomb, where Alexander and his aide Dr. Kavon leave Solo tied under a descending scimitar while Illya and Tracey are hanging over a bottomless pit with a candle burning their rope; to Alexander's farm in Virginia, where Illya is nearly cut in two by various farm implements.moreless