Both Connor Trinneer and John Billingsley who played Deputy Woolgar and Ellis Mars in the episode, respectively, starred together in the series, Star Trek: Enterprise.
Goof: O'Laughlin wouldn't have been able to use a touchscreen phone to take the picture of the bloody fingerprint while wearing latex gloves.
We find out that Lisbon was raised in Chicago, her mother was a nurse and father was a fireman. We also find out the names of two of her brothers, Thomas and James.
Christina Cox (Delinda Lecure) also guest starred in "Bones" episode titled "Death in the Saddle". She played a woman (Annie Oakley) who was involved in S&M acts with horse theme.
We learn the names of Jane's wife and daughter in this episode. His wife's name was Angela and his daughter's name was Charlotte Anne.
Tyger! Tyger! burning bright
In the forests of the night,
What immortal hand or eye
Could frame thy fearful symmetry?
These lines said by Red John and Patrick Jane are the first stanza of William Blake's poem "The Tyger" (from Songs of Experience). The first two lines describe the chaos and evil "the Tyger" creates in mankind, while the second two lines are musing about the creator of "the Tyger".
Hightower: She likes you, that one.
Jane: Which one?
Hightower: The blonde one.
It's obvious from the events in the episode that Hightower is referring to the character Kristina Frye, but that character is a redhead, not a blonde.
At the crime scene, the Sheriff explains that there were no usable prints on the fire extinguisher. However, during the murder scene, the killer is wearing no gloves at all and can be seen firmly holding the fire extinguisher with both hands.
The chess game is (ECO A13) English opening, Agincourt variation.
The title, when translated from numbers to letters, spells R-E-D.
When Jane walks into the Draber's warehouse with Lisbon, he is wearing his jacket, then in the container, he isn't wearing it, nor does he carry it out when they walk off with the kid and the goat. Yet when they arrive at the courthouse, he has it with him again.
As Agent Cho is ending his interview with Griffin Wells, he states "You'll be the richest man in Folsom."
Folsom is a prison run by the California Department of Corrections and Rehabilitation in California State. It is located in the city of Folsom, 20 miles (32 km) northeast of the state capital of Sacramento.
When Dr. Seberg finds the opened Cryptohansa B vial she stops Dr. Welks and Harken from opening the door, because she knows the virus must be contained within the chamber. Seberg responds to Jane's question that the killer would have taken the antidote in advance of opening the vial, the only way it will work. Although having taken the antidote protected them, it is never explained how the killer managed to leave the contaminated chamber without releasing the virus.
At the start of the episode, when Cho is given the address of the murder, the line we hear is "1300 Summit Street" while the closed-captioning reads "3700 Heller Way."
Later at the start of Crystal's interrogation, Lisbon's first line is "Where did you get the drugs?" while the closed-captioning reads "We don't really care about the drugs."
The episode's title, "Redline," is an automotive term that refers to the maximum revolutions per minute (RPM) an engine may operate without damage to the engine itself. The tachometer, an instrument resembling a speedometer, shows the engine's RPM and displays the data with a needle and numbers on a dial. Once the engine reaches maximum RPM, the digits are colored red and separated from the safe RPM with a red line.
"Gonna Make You Sweat (Everybody Dance Now)" by C+C Music Factory (Jane and Lisbon show up at the reunion)
"Macarena" by Los Del Río (Played at the reunion)
"Here Comes the Hotstepper" by Ini Kamoze (Rigsby arrives at the reunion)
"More Than Words" by Extreme (Jane and Lisbon dance)
Music: The song sung in the beginning is an Irish ballad called "Danny Boy"
"Darkening Sky" by Peter Bradley Adams
"Prelude In C Major" by Johann Sebastian Bach (At the doctor's office)
"Amazing Grace" originally by John Newton (Sung by Rigsby)
In the scene where Bosco and the other agents are found, Lisbon goes to Bosco and immediately checks for a pulse. This is the incorrect sequence of steps. The current ABC's of the the American Heart Association are: First, check for open Airway; second, check for Breathing; third, check Circulation(pulse). Not only was Lisbon's pulse check out of sequence, she seems to indicate (barely audible) that Bosco has a pulse then begins to give unnecessary chest compressions on a beating heart. Her attention should have been directed at his airway and breathing since it appeared he wasn't breathing. Even if Bosco had no pulse, the airway and breathing should be checked first.