All fiction is autobiographical, but... there are lines that must not be crossed, specifically the line over to flagrant narcissism.
In this and other recent episodes, Josh Schwartz's character Seth Cohen has become as repulsively narcissistic as Kevin Williamson's character Dawson Leery.
Schwartz is clearly a very talented writer. His dialogue is masterful. The series as a whole is outstanding. But come on, exercise a little restraint. No one wants to listen to Seth Cohen's endless egocentric whining about "Me, me, me!"