The good ol' Hanna-Barbera days, that's what I first think of with the original Powerpuff Girls.
I say they are iconic, because, to me personally, it is ONE their best shows to date, I'm not particularly sure it is THEE best though.
One of the main reasons I say it is so great, is because of all the wonderful collection of villains we got from it.
From my memory of watching this show as a kid, there had to have been at least 20 villains in the entire series, which makes it all the more engaging as a show.
The mayor, is honestly one of the funniest characters I have watched so far on a show from Cartoon Network.
This is a very memorable show, and it deserves to be back on TV.